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308-nm excimer laser for the treatment of localized vitiligo


, : 308-nm excimer laser for the treatment of localized vitiligo. International Journal of Dermatology 42(8): 658-662

Vitiligo is commonly treated with PUVA, and more recently, narrow-band UVB (NBUVB) phototherapy. Given the proximity of the wavelengths of NBUVB (311 nm) and the excimer laser (308 nm), we undertook a clinical trial to test the efficacy of this device. Twice-weekly 308-nm UV-B radiation was given to selected vitiligo lesions for a maximum of 60 treatments. These lesions had been unsuccessfully treated previously with at least one other method of treatment. Initial doses were 100 mJ/cm2 with increments of 10-25%. Improvement was assessed on a visual scale via serial photographs. Subjects tolerated the treatment well. Improvement varied with body site. After 60 treatments, lesions on the hands and feet showed grade 2 improvement in 2/10 subjects and grade 1 in 8/10. For the axillae, there was grade 4 improvement in 1/3 subjects and grade 2 improvement in 2/3 by treatment 60. The face demonstrated the most rapid repigmentation with grade 4 repigmentation seen in 3/5 subjects by 40 treatments and grade 3 in 2/5 by 30 treatments. There were no adverse effects. The user-friendly 308-nm excimer laser allows targeted treatments of localized vitiligo.

US$29.90

PMID: 12890118


Other references

Yang XianLe; Zheng ZongLin, 2007: The application status and strategy of fishery medicine in China. The status of fishery medicine in prevention and cure of fish and shellfish disease, status of research, management, usage of fishery drug in China were reviewed in this article, and also the problems in basic theory, market criterion and safe app...

Bernhard, S.A.; Gutfreund, H., 1965: The optical detection of transients in trypsin- and chymotrypsin-catalyzed reactions. Proceedings of the National Academy of Sciences of the United States of America 53(6): 1238-1243

Buettner, K.J.K.; Kern, C.D., 1965: Evaluation of infrared surface signals received by weather satellites. Proceedings of the Conference on the feasibility of conducting oceanographic explorations from aircraft, manned orbital and lunar laboratories: Oceanography from space, Woods Hole, Mass , 24-28 August, 1964

Kaplan, J., 1978: Modulation of lysosomal enzyme levels in cultured cells effects of alterations in cell density balanced growth and endocytosis. Factors which influence lysosomal enzyme accumulation in cultured cells were studied. In cell types of both fibroblast (3T6) [mouse fibroblast] and epithelial (HeLa) [human cervical carcinoma] origin, acid phosphatase and .beta.-N-acetylglucosamin...

Stander, L.H.; Beskin, C.A.; Acree, P.W.; Martin, H., 1962: Postresection empyema in tuberculosis. Empyema follow-ing pulmonary resection for tuberculosis is an uncommon but serious complication. In a consecutive series of 495 patients who had varied resectional procedures, it occurred in 20. This complication resulted in protracted hospital st...

Cvancara, R., 1964: Growth of mixed broadleaved stands. Presents the results of observations made so far on permanent sample plots established in 1956 in 20-year Beech stands, and 34-year mixed stands, mainly Beech/Oak/Hornbeam, in Kostelec-nad-Cernymi Lesy (central Czechoslovakia). The aim is to make...

Houang, E.T.; Williams, C.J.; Wrigley, P.F., 1976: Acute Listeria monocytogenes osteomyelitis. The presentation and management of a case of acute Listeria monocytogenes osteomyelitis in a lady with acute lymphoblastic leukaemia are described. The literature on Listeria infection is briefly reviewed, and the importance of scrutinizing diphth...

Qin, F.Z.; Zhao, R.R.; Zhu, L.; Wang, W.Z.; Wu, B.W., 1995: Effects of dopexamine on the electrophysiologic changes during myocardial ischemia and comparison with fenoldopam and procaterol. The effects of dopexamine (DPX), a new dopamine receptor agonist, on transmembrane potential and effective refractory period (ERP) of isolated guinea pig ventricular muscle superfused either with hypoxia or mimic ischemia perfusates were investiga...

Dellimore, K.H.; Scheffer, C.; Smith, J.; Van Den Heever, D.J.; Lloyd, D.L., 2016: Evaluating the influence of ventilation and ventilation-compression synchronization on chest compression force and depth during simulated neonatal resuscitation. To investigate the influence of ventilation and ventilation-compression synchronization on compression force and sternal displacement during simulated neonatal cardiopulmonary resuscitation (NCPR) on an infant manikin. Five Neonatal Resuscitation...

Guan PeiCong; Liu HouCheng; Chen YuDi, 2000: Studies on characteristic of NPK absorption by asparagus bean. The characteristics of N, P and K uptake were studied in vine asparagus beans (VAB) V. unguiculata subsp. sesquipedalis cv. Jinsui white pod (WB), Xingqing green pod (GB) and dwarf asparagus bean (DAB) were studied. Nutrient uptake was in the orde...