geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A DNA element recognised by the molybdenum-responsive transcription factor ModE is conserved in Proteobacteria, green sulphur bacteria and Archaea


, : A DNA element recognised by the molybdenum-responsive transcription factor ModE is conserved in Proteobacteria, green sulphur bacteria and Archaea. Bmc Microbiology 3(): 24-24

The transition metal molybdenum is essential for life. Escherichia coli imports this metal into the cell in the form of molybdate ions, which are taken up via an ABC transport system. In E. coli and other Proteobacteria molybdenum metabolism and homeostasis are regulated by the molybdate-responsive transcription factor ModE. Orthologues of ModE are widespread amongst diverse prokaryotes, but not ubiquitous. We identified probable ModE-binding sites upstream of genes implicated in molybdenum metabolism in green sulphur bacteria and methanogenic Archaea as well as in Proteobacteria. We also present evidence of horizontal transfer of nitrogen fixation genes between green sulphur bacteria and methanogenic Archaea. Whereas most of the archaeal helix-turn-helix-containing transcription factors belong to families that are Archaea-specific, ModE is unusual in that it is found in both Archaea and Bacteria. Moreover, its cognate upstream DNA recognition sequence is also conserved between Archaea and Bacteria, despite the fundamental differences in their core transcription machinery. ModE is the third example of a transcriptional regulator with a binding signal that is conserved in Bacteria and Archaea.

US$19.90

PMID: 14641908

DOI: 10.1186/1471-2180-3-24


Other references

Kovalev, V.A., 1993: Lidar measurement of the vertical aerosol extinction profiles with range-dependent backscatter-to-extinction ratios. An iterative lidar-signal inversion method is presented that is valid for two-component (molecular andaerosol) scattering atmospheres. The iterative procedure transforms the original lidar signal, thereby making it possible to use the lidar-equati...

Mcmartin, A., 1934: The Locust Fungus. Its Artificial Cultivation. Failure to produce artificial cultures of Empusa grylli taken from dead locusts has been attributed to its nature as an obligate parasite, existing only on living insects. In recent experiments in Natal, however, growth of the fungus was obtained...

Cooke R.G.; Down J.G., 1971: Coloring matters of australian plants part 16 minor constituents of dianella revoluta m and stypandra grandis m. Australian Journal of Chemistry 24(6): 1257-1265

Tilly, K.; Campbell, J., 1993: A Borrelia burgdorferi homolog of the Escherichia coli rho gene. Nucleic Acids Research 21(4): 1040-1040

Pulawska Z., 1973: The parenchymo vascular cambium and its derivative tissues in stems and roots of bougainvillaea glabra nyctaginaceae. Acta Societatis Botanicorum Poloniae 42(1): 41-61

McCullough, D.L.; Leopold, G.R., 1976: Diagnosis of retroperitoneal fluid collections by ultrasonography: a series of surgically proved cases. A total of 18 patients with a variety of retroperitoneal fluid collections are presented. Etiologic factors and culture results are discussed. Ultrasound was the single most valuable diagnostic study. Because of its accuracy and non-invasiveness i...

Murgov I.D.; Zaitseva Z.M., 1973: Effect of the components of the nutritive medium on the biosynthesis of lysine by the homo serine deficient mutant brevibacterium flavum strain 178. Prikladnaya Biokhimiya i Mikrobiologiya 9(3): 356-361

Cooley K.R.; Hansen C.L.; Jensen D.T., 1991: Erosion potential of Pacific Basin precipitation. Pages 539-545 1991

Liu, H.Y.; Zhang, M.Q.; Wang, R.X.; Yang, G.X.; Sun, Y.D.; Liu, Q.O., 1989: Experiences in the treatment of electrical burns covering deep wounds with various tissue flaps. From 1979 to 1986, 121 patients with electrical burns were admitted to our, unit (6% of all the burned patients admitted during that period). Of these cases 64 were regarded as having deep burns (e.g. burns which injured muscles, tendons, nerves,...

Gora, A., 1983: Effect of two methods of two-way water regulation on important soil parameters in the controlled zone of Schwarzstaugley soils. Archiv fur Acker und Pflanzenbau und Bodenkunde7(12): 773-777