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A study on relationship between rat brain tissues hurts of the gas explosion and the expression of protein kinase CamRNA and c-fos gene.

, : A study on relationship between rat brain tissues hurts of the gas explosion and the expression of protein kinase CamRNA and c-fos gene.. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 23(1): 24-26

To explore relationship between rat brain tissues hurts of gas explosion and the expression of Protein Kinase C alpha mRNA. Build up rat hurt model of gas explosion. In Situ Hybridization (IDH) technique was used to test Protein Kinase C alpha mRNA. Immunohistochemical Assays (IHA) was used to determine c-fos gene protein. Only a little a mount expression of PKC alpha mRNA and c-fos of the control group was detected. The expression of the cerebral cortex and hippocampus of PKC alpha mRNA 24 h, 48 h and the 48 h increased obviously, and the 48 h reached the peak of expression; (t = 4.12 P < 0.01). The expression of c-fos protein of the cerebral cortex and hippocampus started to increase obviously at 0.5 h and the 4 h reached the peak, then the strength lowered gradually and the expression level came back normal level on fifth day. The anoxia of brain tissues due to the gas explosion may promote the expression of PKCamRNA, and PKCamRNA could regulate the expression of the gene of c-fos. Both PKCamRNA and the gene of c-fos are involved in harmful processes to the nerve cells.


PMID: 15748507

Other references

Anonymous, 1974: Infectious process complicating renal transplantation. Clinical conference. Postgraduate Medicine 56(7): 109-13, 115

Krcmery, V.; Ferencik, M.; Duchon, T.; Niznansky, F., 1958: Effect of antibacterial substances on the metabolism of Brucella strains. VI. Effect of bacitracin.. VI. The variability of the effect of bacitracin on the metabolic processes in brucella strains appeared to indicate its inefficacy against this group. In one Br. melitensis strain it produced a decrease in glucose, pyruvate, alanine, asparagine an...

Hammarström, S.; Lagercrantz, R.; Perlmann, P.; Gustafsson, B.E., 1965: Immunological studies in ulcerative colitis. II. "Colon" antigen and human blood group A- and H-like antigens in germfree rats. Sera from patients with ulcerative colitis contain antibodies which hemagglutinate sheep red cells, sensitized with phenol-water extracts from. colon, cecum, or feces of germfree rats. Minor concentrations of such antibodies are also present in a...

Usui, T.; Hara, M.; Satoh, H.; Moriyama, N.; Kagaya, H.; Amano, S.; Oshika, T.; Ishii, Y.; Ibaraki, N.; Hara, C.; Kunimi, M.; Noiri, E.; Tsukamoto, K.; Inatomi, J.; Kawakami, H.; Endou, H.; Igarashi, T.; Goto, A.; Fujita, T.; Araie, M.; Seki, G., 2001: Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis. Proximal renal tubular acidosis associated with ocular abnormalities such as band keratopathy, glaucoma, and cataracts is caused by mutations in the Na(+)-HCO(3)(-) cotransporter (NBC-1). However, the mechanism by which NBC-1 inactivation leads to...

Isacson, O.; Deacon, T.W.; Pakzaban, P.; Burns, L.H.; Galpern, W.R.; Dinsmore, J.; Tatter, S.B.; Leblanc, C.; Park, J., 1994: Long distance graft growth of fetal donor glial fibers inside host white matter axonal tracts but not into axonal grey matter target zones. Society for Neuroscience Abstracts 20(1-2): 9

Fontaine C.T.; Bruss R.G.; Sanderson I.A.; Lightner D.V., 1975: Histo pathological response to turpentine in the white shrimp penaeus setiferus. Journal of Invertebrate Pathology 25(3): 321-330

Roy, B.A.; Coulson, T.; Blaser, W.; Policha, T.; Stewart, J.L.; Blaisdell, G.Kai.; Güsewell, S., 2011: Population regulation by enemies of the grass Brachypodium sylvaticum: demography in native and invaded ranges. The enemy-release hypothesis (ERH) states that species become more successful in their introduced range than in their native range because they leave behind natural enemies in their native range and are thus "released" from enemy pressur...

Willens, J.S., 2012: Why does it take so long to process my manuscript?. Pain Management Nursing 13(2): 69-69

Li, S.; Sloboda, D.M.; Moss, T.J.M.; Nitsos, I.; Polglase, G.R.; Doherty, D.A.; Newnham, J.P.; Challis, J.R.G.; Braun, T., 2013: Effects of glucocorticoid treatment given in early or late gestation on growth and development in sheep. Antenatal corticosteroids are used to augment fetal lung maturity in human pregnancy. Dexamethasone (DEX) is also used to treat congenital adrenal hyperplasia of the fetus in early pregnancy. We previously reported effects of synthetic corticoster...

Lazic, Z., 1962: Hybrid grain sorghums and the possibility of their cultivation in Vojvodina. Information on the earliness and yield of introduced hybrids in comparison with the sweet sorghum Novosadski is given.