+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Addition reactions of ROPHy/SOPHy oxime ethers: asymmetric synthesis of nitrogen containing compounds

, : Addition reactions of ROPHy/SOPHy oxime ethers: asymmetric synthesis of nitrogen containing compounds. Chemical Communications: 1341-1351

Oxime ethers prepared from (R)- or (S)-O-(1-phenylbutyl)hydroxylamine (ROPHy or SOPHy) are versatile intermediates for the asymmetric synthesis of a range of nitrogen containing compounds including simple amines, 1,2-aminoalcohols, alpha- and beta-amino acids, heterocyclic building blocks of natural products, piperidine alkaloids, lactams, 5- to 8-membered ring nitrogen heterocycles, imino-sugars, and chiral ferrocene based receptors.


PMID: 15179459

DOI: 10.1039/b400079j

Other references

Desmonts, T.; Morer, S.; Fondeville, M., 1960: Tetanus and bullous eruptions due to viruses. Revue de Pathologie Generale et de Physiologie Clinique 60: 245-247

Karmazyn, M.; Gan, X.Tracey.; Rajapurohitam, V., 2014: The potential contribution of circulating and locally produced leptin to cardiac hypertrophy and failure. Leptin is a 16 kDa peptide that was first identified in 1994 through positional cloning of the mouse obesity gene. Although the primary function of leptin is to act a satiety factor through its actions on the hypothalamus, it is now widely recogni...

Wen, J.; Xia, Q.; Wang, C.; Liu, W.; Chen, Y.; Gao, J.; Gong, Y.; Yin, B.; Ke, Y.; Qiang, B.; Yuan, J.; Peng, X., 2010: Dok-5 is involved in cardiomyocyte differentiation through PKB/FOXO3a pathway. The insulin receptor substrate (IRS) family plays important roles in cellular growth, signaling, and survival in the brain. We identified IRS6/Dok-5, a member of the IRS family, also expressed in heart. Dok-5 expression level significantly increas...

Wolsan M., 1984: Dental abnormalities in the pine marten martes martes carnivora mustelidae from poland. Dental abnormalities found in 8 out of 220 skulls of pine martens from Poland are described and attempts are made to explain their occurrence.

Nogueira, Fátima.; Diez, A.; Radfar, A.; Pérez-Benavente, S.; do Rosario, V.E.; Puyet, A.; Bautista, Jé.M., 2010: Early transcriptional response to chloroquine of the Plasmodium falciparum antioxidant defence in sensitive and resistant clones. Resistance to chloroquine (CQ) in Plasmodium falciparum has a major impact on malaria control worldwide. To gain insight into early parasite stress response, mRNA expression profiles were determined for a set of 10 antioxidant defence genes in syn...

Khatkar, M.S.; Sethi, R.K., 1995: Influence of body size on milk production performance in Murrah buffaloes. Performance records of 215 Murrah buffaloes, calved during 1990-91 at CIRB, Hisar, were studied to evaluate the influence of body weight (<400, 400-450, 451-500, 510-550 and >550 kg) on production performance independent of the effect due to...

Bones, D.L.; Plane, J.M.C.; Feng, W., 2015: Dissociative Recombination of FeO(+) with Electrons: Implications for Plasma Layers in the Ionosphere. The dissociative recombination (DR) of FeO(+) ions with electrons has been studied in a flowing afterglow reactor. FeO(+) was generated by the pulsed laser ablation of a solid Fe target, and then entrained in an Ar(+) ion/electron plasma where the...

Vetreno, R.P.; Yaxley, R.; Paniagua, B.; Johnson, G.Allan.; Crews, F.T., 2016: Adult rat cortical thickness changes across age and following adolescent intermittent ethanol treatment. NlmCategory="UNASSIGNED">Human studies have established that adolescence is a period of brain maturation that parallels the development of adult behaviors. However, little is known regarding cortical development in the adult rat brain...

Eikmeier G., 1987: Priapism under major tranquilizer therapy. Nervenarzt 58(12): 771-772

Olthoff J.C.; Boylan W.J., 1991: Carcass merit of market lambs from purebred and crossbred finnsheep ewes. Carcass merit determines the quality of output from a sheep production system. Carcass trait data were obtained on 303 lambs in three breeding groups: purebred Finnsheep (Finn), Suffolk, Targhee and Dorset; F1 Finn crossbreds; and multiple crosses...