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Antithrombotic and thrombolytic therapy: from evidence to application: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

, : Antithrombotic and thrombolytic therapy: from evidence to application: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126(3 Suppl): 688s-696s

This chapter about implementation strategies for practice guidelines is part of the 7th ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. Grade 2 suggests that feasibility, acceptability and cost related to implementation strategies may lead to different choices depending on the practice setting (for a full understanding of the grading see Guyatt et al, CHEST 2004; 126:179S-187S). To encourage uptake of guidelines to reduce thrombosis, we recommend that appreciable resources be devoted to distribution of educational material (Grade 2B). We suggest that few resources be devoted to educational meetings (Grade 2B), to audit and feedback (Grade 2B), or to educational outreach visits (Grade 2B) to encourage uptake of the guidelines. We suggest that appreciable resources be devoted to computer reminders (Grade 2A) and to patient-mediated interventions (Grade 2B) to encourage uptake of the guidelines. This review suggests that there are few implementation strategies that are of unequivocal, consistent benefit, and that are clearly and consistently worth resource investment. Fully informed decisions will require additional research to identify effective guideline implementation strategies to optimize antithrombotic and thrombolytic therapy.


PMID: 15383490

DOI: 10.1378/chest.126.3_suppl.688S

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Corday, E.; Swan, H.J.; Lang, T.W.; Goldman, A.; Matloff, J.M.; Gold, H.; Meerbaum, S., 1970: Physiologic principles in the application of circulatory assist for the failing heart. Intraaortic balloon circulatory assist and venoarterial phased partial bypass. American Journal of Cardiology 26(6): 595-602

Zheng, L.; Azar, D., 2015: Angle-closure glaucoma following periorbital botulinum toxin injection. Clinical & Experimental Ophthalmology 42(7): 690-693

Meyer, K., D.; Paul, V., J., 1992: Intraplant variation in secondary metabolite concentration in three species of Caulerpa (Chlorophyta: Caulerpales) and its effects on herbivorous fishes. Three species of tropical green algae, Caulerpa spp., were examined for intraspecific variation in the concentrations of their secondary metabolites. Individual plants were collected from coral reef areas on Guam, divided into 2 plant portions (up...

Orozco, A.F.; Bischoff, F.Z.; Horne, C.; Popek, E.; Simpson, J.Leigh.; Lewis, D.E., 2006: Hypoxia-induced membrane-bound apoptotic DNA particles: potential mechanism of fetal DNA in maternal plasma. Fetal DNA is found in the plasma of pregnant women that appears to be stable for PCR amplification. Although the underlying mechanism giving rise to this DNA in plasma remains unclear, the source of these fragments may be from apoptotic bodies (Ap...

Gilbert, CMcL., 1937: A remarkable North American species of the genus Phaenocora. Zeitschrift fuer Morphologie und Oekologie der Tiere Berlin, 33: 53-71

Leonard, OS., 1946: The immunizing effect in the action of trypanocidal drugs. Science Lancaster, 104: 556

Roots, H.; Ranatunga, K.W., 2008: An analysis of the temperature dependence of force, during steady shortening at different velocities, in (mammalian) fast muscle fibres. We examined, over a wide range of temperatures (10-35 degrees C), the isometric tension and tension during ramp shortening at different velocities (0.2-4 L(0)/s) in tetanized intact fibre bundles from a rat fast (flexor hallucis brevis) muscle; fi...

Brown, R.Malcolm, Jr, 2000: Recent update in cellulose biosynthesis and structure. In Vitro Cellular & Developmental Biology Animal 36(3 Part 2): 19 A, March

Frank, K.D.; Pesek, J., 1973: Influence of applied nitrogen on the performance of 23 orchardgrass (Dactylis glomerata L.) varieties. In field trials in 1966-7, 11 early, 6 medium and 6 late cocksfoot cultivars were given, 0, 270 or 540 kg N, 20 kg P and 110 kg K/ha. The higher N rate gave increases in herbage yield above those obtained with the lower rate only in the 3rd harves...

Hayward, J.R., 1970: Editorial. Anesthesia and hospital training. Journal of Oral Surgery 28(3): 167-167