+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

C-24 stereochemistry of marine sterols: (22E)-24-(isopropenyl)-22-dehydrocholesterol and 24-isopropenylcholesterol

, : C-24 stereochemistry of marine sterols: (22E)-24-(isopropenyl)-22-dehydrocholesterol and 24-isopropenylcholesterol. Chemical & Pharmaceutical Bulletin 54(10): 1473-1477

The C-24 configuration of (22E,24xi)-24-isopropenyl-22-dehydrocholesterol (1), which was recently isolated from the Colombian Caribbean sponge, Topsentia ophiraphidites, was investigated. Synthesis of the stereodefined (24R)- and (24S)-(22E)-24-isopropenyl-22-dehydrocholesterols (1a, 1b) followed by (1)H- and (13)C-NMR data comparison of these sterols established the (24R)-configuration of 1. In addition, (24R)- and (24S)-24-isopropenylcholesterols (2a and 2b) were also synthesized and their NMR data are provided. The C-24 configurations of the samples of 24-isopropenylcholesterol reported previously are discussed.


PMID: 17015996

Other references

Dormuth, C.R.; Maclure, M.; Carney, G.; Schneeweiss, S.; Bassett, K.; Wright, J.M., 2009: Rosiglitazone and myocardial infarction in patients previously prescribed metformin. Rosiglitazone was found associated with approximately a 43% increase in risk of acute myocardial infarction (AMI) in a two meta-analyses of clinical trials. Our objective is to estimate the magnitude of the association in real-world patients previ...

Spaide, R.F.; Fisher, Y.; Ober, M.; Stoller, G., 2006: Surgical hypothesis: inner retinal fenestration as a treatment for optic disc pit maculopathy. Retina 26(1): 89-91

Magin-Lachmann, C.; Hahn, S.; Strobel, H.; Held, U.; Löwer, J.; Löwer, R., 2001: Rec (formerly Corf) function requires interaction with a complex, folded RNA structure within its responsive element rather than binding to a discrete specific binding site. It was recently reported that the human endogenous retrovirus HTDV/HERV-K encodes the regulatory protein Rec (formerly designated Corf), which is functionally equivalent to the nuclear export adapter proteins Rev of human immunodeficiency virus an...

Jairo A.P.redes; Alex H.B.rbat; Sergio Oller, 2011: A compression–tension concrete damage model, applied to a wind turbine reinforced concrete tower. Structures subjected to cyclic loads show alternative tension compression stress states; in such a case, even if certain damage (fracture) is reached during the tension cycle, the computational model of the structure should maintain its capacity t...

Adams, R., 1994: Doing more with less: new supply program cuts total delivered costs. Materials Management in Health Care 3(8): 58-60

Anonymous, 2001: Boy's HIV may impede his ability to care for himself, judge rules. Two Wisconsin day care centers settled a discrimination lawsuit after a Federal judge rejected their claims that HIV is not covered by the Americans with Disabilities Act (ADA). Kiddie Ranch and Happy Time Day Care Center refused to admit an HIV-p...

Brendonck, L.; Riddoch, B.J., 1999: Wind-borne short-range egg dispersal in anostracans. Evidence is provided for the first time that at least part of the egg bank of the southern African fairy shrimp Branchipodopsis wolfi is dispersed over short distances by wind. A total of 423 sticky surfaces were mounted around and between individ...

Benyoussef, A.; Chakib, H.; Ez-Zahraouy, H., 2003: Anisotropy effect on two-dimensional cellular-automaton traffic flow with periodic and open boundaries. Using computer simulations we investigate, in a version of the Biham-Middleton-Levine model with random sequential update on a square lattice, the anisotropy effect of the probabilities of the change of the motion directions of cars, from up to ri...

Jani, M., 1982: Control of Varoa jacobsoni infestation of honeybees, Slovakia.1. Vcelar 56(8): 180-181

Fujiwara, Y.; Uehara, Y.; Ichihashi, M.; Nishioka, K., 1985: Xeroderma pigmentosum complementation group F: more assignments and repair characteristics. Photochemistry and Photobiology 41(5): 629-634