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Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer

, : Challenges and opportunities to the design and implementation of chemoprevention trials for prostate cancer. Urologic Oncology 21(1): 73-78

Since 1991 and the activation of the Prostate Cancer Prevention Trial as well as similar prevention studies in several other organ sites, the interest in prostate cancer prevention has increased substantially. Despite such interest, the challenges to prevention trials-in design, implementation, prioritization, and allocation of resources-are substantial. Simultaneously, there has been an explosion in new targets and agents that may have an effect in the prevention of this disease. In this manuscript, we discuss these challenges to the study of prostate cancer prevention and provide a blueprint for prioritization of future studies.


PMID: 12684131

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