+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Conformation and recognition control of peptide ribonucleic acid containing pyrimidine/purine mixed sequence

, : Conformation and recognition control of peptide ribonucleic acid containing pyrimidine/purine mixed sequence. Nucleic Acids Research. Supplement: 229-230

Peptide ribonucleic acids (PRNA), tethering 5'-amino-5'-deoxyribonucleoside as a recognition moiety for RNA/DNA, have been designed and synthesized, as a novel nucleic acid model. External switching of the recognition behavior of PRNA containing not only pyrimidine nucleobase but also purine nucleobase, with complementary oligomeric DNA/RNA has been demonstrated for the first time through both the orientational switching of the nucleobase of PRNA and electrostatic repulsion between borate ester anion of PRNA and phosphodiester anion of DNA/RNA, induced by added borates.


PMID: 12836348

Other references

Walker, B.F., 1995: Evidence based chiropractic. Comsig Review 4(3): 74-79

D.A.geli, S.; Fandella, A.; Conconi, M.T.resa; Anselmo, G.; Parnigotto, P.P.olo, 1994: Growth, morphology, and morphometry of human hypertrophic prostate cells treated with suramin in vitro. This work studies the effects of suramin on the growth and morphology of cell strain U285, obtained from human prostate hypertrophic tissue and cultured in vitro. The FRAME cytotoxicity test was performed to evaluate the inhibition of growth induc...

Rockwell, S., 1977: Influence of a 1400-gauss magnetic field on the radiosensitivity and recovery of EMT6 cells in vitro. EMT6 mouse mammary tumour cells in vitro were exposed to an almost uniform 1400-gauss magnetic field during or after irradiation with 120 kV X-rays. Exposure of unirradiated control cultures to this field for up to 48 hours did not alter the viabi...

Johnston, W.K.; Unrau, P.J.; Lawrence, M.S.; Glasner, M.E.; Bartel, D.P., 2001: RNA-catalyzed RNA polymerization: accurate and general RNA-templated primer extension. The RNA world hypothesis regarding the early evolution of life relies on the premise that some RNA sequences can catalyze RNA replication. In support of this conjecture, we describe here an RNA molecule that catalyzes the type of polymerization ne...

Schaeflein J.W.; Schlesinger T.; Stephens S.O.; Neblett D.L.; Haymond H.R.; Harwood G.E., 1978: Some observations on iridium 192. Vaeth, Jerome M (Ed ) Frontiers Of Radiation Therapy And Oncology, Vol 12 Renaissance Of Interstitial Brachytherapy 12th Annual San Francisco Cancer Symposium San Francisco, Calif , Usa Mar 4-5, 1977 Vi+178p Illus S Karger: Basel, Switzerland; New York, N Y , Usa Isbn30-8055-2706-3 13-20

Kalyanpur, A.; Schwartz, D.S.; Fields, J.M.; Rayes-Mugica, M.; Keller, M.S.; Gosche, J., 1997: Renal medulla carcinoma in a white adolescent. Ajr. American Journal of Roentgenology 169(4): 1037-1038

Duranti, A.; Cuocolo, L., 1982: Studies on nitrogen fertilizing of eggplant. Three rates of N (100, 200 and 400 kg/ha N as NH4NO3) and seven application dates were compared. N did not affect the fruiting time of eggplants (cv. Violetta Lunga di Napoli) but the size and number of fruits increased with the amount applied. Th...

Zhu, Q.; Sun, Y.; Cui, Y.; Ye, K.; Yang, C.; Yang, D.; Ma, J.; Liu, X.; Yu, J.; Ge, H., 2017: Clinical outcome of tyrosine kinase inhibitors alone or combined with radiotherapy for brain metastases from epidermal growth factor receptor (EGFR) mutant non small cell lung cancer (NSCLC). This study compared treatment outcomes between TKI monotherapy and TKI administration combined with brain radiotherapy (TKI + RT) in 133 non-small cell lung cancer (NSCLC) patients with brain metastasis (BM). We also evaluated the association of d...

Lumsden, L.L.; Lumsden, L.L., 2006: The Public Health Program of the United States Training Corps for Women. 1919. Public Health Reports 121 Suppl 1: 133-5; Discussion 132

Rao, K.P.C., 1997: Simulation modeling. The PERFECT (Productivity, Erosion and Runoff Functions to Evaluate Conservation Techniques) model and its application are discussed.