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Coral as a carrier for recombinant human bone morphogenetic protein-2

, : Coral as a carrier for recombinant human bone morphogenetic protein-2. Chinese Medical Sciences Journal 14(2): 125-128

By combining coral with recombinant human bone morphogenetic protein-2 (rhBMP-2), rhBMP-2/coral composite was obtained in this study. Following implantation of the composite into the muscle pouches of mice, cartilage growth was induced in the pores or on the surface of the implants at one week, woven bone at three week and lamellar bone with bone marrow at six week, and coral was absorbed partially. The induced formation of endochondral bone was time-related and rhBMP-2 dose-related. The results of this study indicate that the composite possesses a superior ability of osteogenesis, and coral acts as one of the most suitable rhBMP-2 slowrelease carriers currently available. The composite will be a new type of bone substitute to be used in orthopaedics and maxillofacial surgery.


PMID: 12901624

Other references

Anonymous, 1973: International Biological Programme. Section PP (Production Processes). World catalogue of Rhizobium collections. Data are listed for about 3000 Rhizobium strains forming root nodules on about 430 species of host plants which have been obtained from 59 collections made in 29 countries. Potential contributors were asked to provide details of the strains of rhi...

Puthussery, J.; Kosel, T.H.; Kuno, M., 2009: Facile synthesis and size control of II-VI nanowires using bismuth salts. Small 5(10): 1112-1116

Guerin, M.V.; Wang, X.J., 1994: Environmental temperature has an influence on timing of the first ovulation of seasonal estrus in the mare. A 10-yr retrospective analysis of the time of onset of seasonal ovulation derived from the records of a Thoroughbred horse stud at latitude 35 degree S revealed a significant variation between years. The onset of seasonal ovulation was closely rel...

Diehm, C.; Jacobsen, O.; Amendt, K., 1993: The effects of tertatolol on lipid profile. Tertatolol is a noncardioselective beta-blocker without intrinsic sympathomimetic activity. In a preliminary 3-month open study, it was shown that T was devoid of any atherogenic effect since HDL-cholesterol (HDL-C) and apoprotein levels did not c...

Hammad, S.M.; Stefansson, S.; Twal, W.O.; Drake, C.J.; Fleming, P.; Remaley, A.; Brewer, H.B.; Argraves, W.S., 1999: Cubilin, the endocytic receptor for intrinsic factor-vitamin B(12) complex, mediates high-density lipoprotein holoparticle endocytosis. Receptors that endocytose high-density lipoproteins (HDL) have been elusive. Here yolk-sac endoderm-like cells were used to identify an endocytic receptor for HDL. The receptor was isolated by HDL affinity chromatography and identified as cubilin,...

Debyser, Z.; Pauwels, R.; Baba, M.; Desmyter, J.; D.C.ercq, E., 1992: Common features in the interaction of tetrahydroimidazo benzodiazepin-2 -one and -thione and 1- methyl-6-. Recently, several classes of compounds have been shown to be potent, selective, and specific inhibitors of human immunodeficiency virus type 1 replication in vitro. These include the tetrahydroimidazo(4,5,1-jk)(1,4)-benzodiazepin-2(1H)-one and -th...

Montoro, C.; Miller-Cushon, E.K.; DeVries, T.J.; Bach, A., 2013: Effect of physical form of forage on performance, feeding behavior, and digestibility of Holstein calves. The physical form of forage may influence rumen development and, consequently, the body weight gain, dry matter (DM) consumption, digestibility, and welfare of dairy calves. The objective of this study was to determine the effect of 2 different ph...

Delius, L., 1968: Psychological and psychotherapeutic aspects in the rehabilitation of heart patients. Zeitschrift für Kreislaufforschung 57(1): 84-87

Miyazaki, T.; Fujiki, H.; Yamamura, Y.; Nakamura, S.; Mori, T., 2007: Tolvaptan, an orally active vasopressin V(2)-receptor antagonist - pharmacology and clinical trials. Tolvaptan is an orally effective nonpeptide arginine vasopressin (AVP) V(2)-receptor antagonist synthesized by Otsuka Pharmaceutical Co., Ltd. In in vitro receptor-binding studies, tolvaptan blocked the binding of [(3)H]AVP to human V(2) receptors...

Nayak, BK.; Gupta, ML.; Das, AK.; Guru, BC., 1986: Sex relation in chupi cocoon of tasar silk insect Antheraea mylitta Drury (Lepidoptera: Saturniidae). Science and Culture, 5210: 349-350