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Critical analysis of pathophysiological, diagnostic and therapeutic aspects of metabolic bone disease in very low birth weight infants


, : Critical analysis of pathophysiological, diagnostic and therapeutic aspects of metabolic bone disease in very low birth weight infants. Jornal de Pediatria 77 Suppl 1: S53-S62

OBJECTIVE: To perform a systematic review on the pathophysiology, diagnosis and approach of metabolic bone disease in very low birth weight infants. SOURCES: Literature review of articles published in Medline within the last twenty years. SUMMARY OF THE FINDINGS: The higher survival of very low birth weight infants was concurrent with the increased incidence of metabolic bone disease. The process of bone mineral acquisition suffers some alterations during the neonatal period, including low bone mineral content at birth, insufficient mineral supply in the neonatal period, and regulatory disorders, which may compromise growth and development on the long run. The diagnosis is based on the association of risk factors, and biochemical and radiological alterations. The early intervention in the neonatal period prevents the development of severe metabolic bone disease, reducing complications during the first year of life. CONCLUSIONS: The early diagnosis of metabolic bone disease allows for early intervention, thus preventing complications that may originate from the alterations in bone mineral acquisition.

US$29.90

PMID: 14676893


Other references

Zaza, G.; Rascio, F.; Pontrelli, P.; Granata, S.; Stifanelli, P.; Accetturo, M.; Ancona, N.; Gesualdo, L.; Lupo, A.; Grandaliano, G., 2014: Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients. Immediately after renal transplantation, patients experience rapid and significant improvement of their clinical conditions and undergo considerable systemic and cellular modifications. However, some patients present a slow recovery of the renal f...

Mauss, V.; Schindler, M., 1998: Records of bees and wasps in the district of Nordfriesland, Schleswig-Holstein Chrysididae, Apidae, Sphecidae, Pompilidae, Vespidae Nachweise von Bienen und Wespen im Kreis Nordfriesland, Schleswig-Holstein Chrysididae, Apidae, Sphecidae, Pompilidae, Vespidae. Bombus. 1 September; 332-34: 134-136

Ochi, H.; Takeda, S., 2014: Bone metabolism and cardiovascular function update. Nerve system and mutual interaction between bone and blood vessel. The identification that nervous system controls bone metabolism through leptin deficient mice studies opened a new field in bone biology. Notably, sympathetic and parasympathetic nerve system regulate bone metabolism. In addition, sensory nerve sy...

Saiapin, I.V., 2005: Training and retraining of military medical cadres during the years of Great Patriotic war. Voenno-Meditsinskii Zhurnal 326(9): 52-54

Sansivero, G.E., 1998: How to withdraw a PICC. Nursing 27(12): 25-25

Fourcade, J.; Guyenot, E., 1957: Compensation rates; legal bases, difficulties in their evaluation. Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale 18(2): 192-200; Discussion, 200-1

Bartsch C.; Dietrich H.; Unterstab A., 1989: The dependence of sonic velocity in sandstones on other petrologic properties. Zeitschrift fuer Angewandte Geologie: , Pages 149-152. 1989.

Abia, R.; Fry, S.C.; Eastwood, M.A., 1996: Metabolic transformations of U-14C-resistant and U-14C-gelatinized bean starch in rat liver and body. The metabolic fate of carbon derived from dietary U-14C-resistant (RS) and U-14C-gelatinized (GS) bean starches was studied in rat liver and body (mainly muscle). Male Wistar Hans rats were fed 20 mg of either GS (43.3 times 10-3 Bq) or RS (47.3 t...

Gallien, L., 1959: Analysis of the effects of steroid hormones on sex differentiation in Amphibia. The examination of experiments reported in the literature leads to the conclusion that steroid hormones in general do not mimic the effect of natural embryonic inductors. Thus the male steroids cause masculinization in the higher Anura but the eff...

Saito, Y.; Matsumura, K.; Shimizu, S.; Ichikawa, Y.; Ochiai, K.; Goto, J.; Tsuji, S.; Shimizu, T., 2006: Pigmentary macular dystrophy in spinocerebellar ataxia type 1. Journal of Neurology, Neurosurgery, and Psychiatry 77(11): 1293-1293