geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Current concepts of metabolic abnormalities in HIV patients: focus on lipodystrophy


, : Current concepts of metabolic abnormalities in HIV patients: focus on lipodystrophy. Aids Reader 13(12 Suppl): S5-13

HIV infection is associated with a number of metabolic abnormalities, including lipodystrophy, a difficult-to-define disorder whose characteristics include hyperlipidemia, insulin resistance, and fat redistribution. Current data suggest that lipodystrophy is caused by multiple factors. Dual-nucleoside reverse transcriptase inhibitor therapy combined with protease inhibitor therapy has been shown to increase the risk of metabolic abnormalities, but susceptibility independent of drug effects has also been shown. While many of the treatments for the broad range of signs and symptoms of lipodystrophy bring about improvements in patient status, none have been demonstrated to bring about a return to baseline levels.

US$29.90

PMID: 14959694


Other references

Christensen, R.O., 1949: Surgical removal of a fibroma and lipoma from the maxilla; report of a case. Journal of the American Dental Association 39(2): 232-232

Simovic, S.; Hui, H.; Song, Y.; Davey, A.K.; Rades, T.; Prestidge, C.A., 2010: An oral delivery system for indomethicin engineered from cationic lipid emulsions and silica nanoparticles. We report on a porous silica-lipid hybrid microcapsule (SLH) oral delivery system for indomethacin fabricated from Pickering emulsion templates, where the drug forms an electrostatic complex with cationic lipid present in the oil phase. Dry SLH mi...

Namkoong, G.; Usanis, R.A.; Silen, R.R., 1972: Age-related variation in genetic control of height growth in Douglas-fir. The development of genetic variances in height growth of Douglas-fir over a 53-year period is analyzed and found to fall into three periods. In the juvenile period, variances in environmental error increase logarithmically, genetic variance within...

Zanini, J.R., 1989: Evaluation of sweet sorghum (Sorghum bicolor (L.) Moench) seeds vigour at different maturity stages. Eleven seed harvests were taken at weekly intervals from field-grown sweet sorghum cv. BR 501 in 1981 commencing at flowering. Max. seed DM and percentage germination were attained with harvest 33 d after flowering and corresponded with black laye...

Natali, J., 1996: Forensic medical implications of vascular injuries and accidents related to the practice of conventional vascular surgery. Three areas are covered: neck surgery, thoracic aorta and abdominal aorta surgery. In neck surgery, cerebral vascular events can occur after endarterectomy of the carotid artery or after resection of carotid loops. These accidents are also seen af...

Currò, M.; Montalto, A.S.; Impellizzeri, P.; Montalto, E.; Risitano, R.; Russo, T.; Perrone, P.; Chirico, V.; Arrigo, T.; Salpietro, C.; Romeo, C.; Ientile, R., 2014: CO(2) pneumoperitoneum induces in vitro hypoxic response culminating in apoptosis of human neuroblastoma cells. The ablative role of minimally invasive surgery (MIS) in neuroblastoma (NB) is still controversial due to the possible CO₂ pneumoperitoneum side-effects on tumor aggressiveness. It is known that CO₂ produces hypoxic condition with changes in t...

Grosse, I.; Buldyrev, S.V.; Stanley, H.E.; Holste, D.; Herzel, H., 2000: Average mutual information of coding and noncoding DNA. One basic problem in the analysis of DNA sequences is the recognition of protein-coding genes. Computer algorithms to facilitate gene identification have become important as genome sequencing projects have turned from mapping to large-scale sequen...

Johansson, E.; Aparisi, T., 1982: Congenital absence of the cruciate ligaments: a case report and review of the literature. Clinical Orthopaedics and Related Research: 108-111

Díaz Trigo, A.; Fierri, A.M., 1967: Observations on tuberculosis patients who are non-adaptable to the hospital environment. Relation to the clinical forms and its constitutional and psychological types. Prensa Medica Argentina 54(24): 1187-1188

Peterson, S.E.; Westra, J.W.; Rehen, S.K.; Young, H.; Bushman, D.M.; Paczkowski, C.M.; Yung, Y.C.; Lynch, C.L.; Tran, H.T.; Nickey, K.S.; Wang, Y-Chieh.; Laurent, L.C.; Loring, J.F.; Carpenter, M.K.; Chun, J., 2012: Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy. Human pluripotent stem cell (hPSC) lines have been considered to be homogeneously euploid. Here we report that normal hPSC--including induced pluripotent--lines are karyotypic mosaics of euploid cells intermixed with many cells showing non-clonal...