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Detection of antibodies to M. leprae in saliva of lepric patients


, : Detection of antibodies to M. leprae in saliva of lepric patients. Klinicheskaia Laboratornaia Diagnostika: 52-54

Saliva of 116 lepric patients were scanned for antibodies in ELISA (with M. leprae cultivated in vitro used as antigen) in order to work out an invasion-free diagnostic tool for lepra. The ELISA findings for "saliva-serum" pairs from same patients showed an increased level of antibodies both in serum and saliva in 39.7% of cases, and matching of results (positive and negative ones) was observed in 73.3% of patients. The increasing level of specific antibodies as observed in intensification of the lepric process in blood serum occurred simultaneously with its increase in saliva. The invasion-free diagnostics of lepra is promising for examinations of contact persons and of population in endemic regions as well as for evaluating the efficiency of the antilepric therapy.

US$29.90

PMID: 15765658


Other references

Wasterlain C.G.; Csiszar E., 1980: Cyclic nucleotide metabolism in mouse brain during seizures induced by bicuculline or di butyryl cyclic gmp. Bicuculline-induced seizures have been used as a model of epilepsy. In adult male C57 black mice, intracortical injection of bicuculline (10 .mu.g) elevated cGMP concentrations and produced contralateral clonic seizures. After i.p. injection, bicu...

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Bally R.J.; Klein R., 1983: Some research works and applications of grouting of fine grained soils in Romania. Pages 127-130 1983

Jones, O.T., 1938: The geology and physiography of the Cambridge District. Report of the British Association for the Advancement of Science London, 108: 1-24

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Kaye, W.; Mancini, M., E.; Giuliano, K., K.; Richards, N.; Nagid, D., M.; Marler, C., A.; Sawyer-Silva, S., 1995: Strengthening the In-Hospital Chain of Survival With Rapid Defibrillation by First Responders Using Automated External Defibrillators: Training and Retention Issues. Study objective: To determine whether staff outside critical care areas who were proficient in basic life support (BLS) could be easily trained to use automated external defibrillators (AEDs) and whether they would retain these skills. Design: Pro...

Bertolani, R.; Rebecchi, L.; Giovanni, I.; Cesari, M., 2011: DNA barcoding and integrative taxonomy of Macrobiotus hufelandi CAS Schultze 1834, the first tardigrade species to be described, and some related species. Within the framework of a DNA barcoding project on tardigrade species, a study was carried out on Macrobiotus hufelandi C.A.S. Schultze 1834, the first formally described tardigrade species. We used samples collected from the type locality and add...

Luigi Butera; Revelli Roberto; Ridolfi Luca, 2001: Experimental evidence of the interaction between piers in the scour process. The problem of mutual interaction between round-nosed piers over a rectangular foundation is studied with respect to different alignments of the flow field. A series of laboratory investigations has been are conducted to study how the scour proces...

Krivosic-Horber, R.; Besse, M.D.; Moreau, D.; Delecroix, M., 1980: Interactions between halogenated anesthetics and adrenaline. Experiments on dogs. Lille Medical 25(7): 336-338