geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Diastolic filling of the right ventricle in patients with arterial hypertension and ischemic heart disease


, : Diastolic filling of the right ventricle in patients with arterial hypertension and ischemic heart disease. Likars'ka Sprava: 33-40

Our objective in this study was to compare particular features of pathogenesis of diastolic dysfunction of the right ventricle (RV) in patients with arterial hypertension (AH), stable exertional angina, and myocardial infarction of the left ventricle (LV) and to establish diagnostic significance thereof. As many as 429 AH patients presenting with different clinical forms of ischemic heart disease (IHD) were examined. Of these, 209 patients presented with stage I to III AH, 105 had functional class (FC) I-III stable exercise-induced angina, 115 patients had acute LF myocardial infarction (MI) verified by clinical findings, changes in ECG, and time-course of activity of myocardial enzymes. The control group was 30 essentially healthy subjects with no signs of cardiovascular and respiratory affections. All examinees underwent Doppler echocardiography as recommended by the American Society of Echocardiography. Measured in the above series were LV wall relative thickness, LV ejection fraction (EF) as recommended by L. Teichholz et al., LV isovolumetric relaxation time (IVRT), peak velocities of early (E) and atrial (A) filling of the heart's ventricles, E/A ratio, early diastolic filling deceleration time (DT) for both transmitral and transtricuspid flows, acceleration time of systolic flow in the pulmonary trunc as an indirect indicator of pressure in it. In AH patients, there was a close direct correlation between indices for filling of both ventricles (E/A ratio, E-wave DT and IVRT) but no significant correlation between indices for RV diastolic function and dimensions of left chambers or LV EF. In AH patients, disturbances in the diastolic function of the heart were at their greatest in eccentric hypertrophy of the myocardium when in the presence of pseudonomal and restrictive indices for LV filling "pseudonormalization" of the transtricuspid flow was being formed. In stable angina and MI, it was LV systolic dysfunction and pulmonary diastolic dysfunction that proved to play a major part in the development of RV diastolic dysfunction, its indices correlating significantly with heart failure and stable angina functional classes.

US$29.90

PMID: 12712606


Other references

Rosenfeld R.G., 1984: Somatomedin c in precocious puberty. Pediatric Researchpart 2: 174a

Min, L.; Wu, G.; Liu, M.; Gao, W.; Ding, J.; Chen, J.; Huang, X.; Wu, H., 2016: Copper-Catalyzed Oxirane-Opening Reaction with Aryl Iodides and Se Powder. Using Se powder as the selenating reagent, the copper-catalyzed double C-Se cross-coupling of aryl iodides, epoxides, and elemental selenium has been developed. This strategy provides a straightforward approach to the synthesis of β-hydroxy pheny...

Simonelli, A.; Bighin, M.; de Palo, F., 2012: Coparenting interactions observed by the prenatal lausanne trilogue play: An Italian replication study. The infant-parent interaction is the focus of interest on early interactive relational models in the triadic perspective. This approach considers the mother-father-child interaction as the matrix of early competences, which start to develop well b...

Maéslińska, D.; Muzylak, M., 1997: Ultrastructure of myelinated fibers of sciatic nerve in acute vincristine intoxication. Numerous clinical reports documented that in some patients vincristine (VCR) may cause a risk for life (stridor) and painful symptoms of acute intoxication. The present study was undertaken to examine ultrastructural changes in the sciatic nerve o...

Spotnitz, H.M.; Cabreriza, S.E.; Wang, D.Y.; Quinn, T.Alexander.; Cheng, B.; Bedrosian, L.N.; Aponte-Patel, L.; Smith, C.R., 2013: Primary endpoints of the biventricular pacing after cardiac surgery trial. This study sought to determine whether optimized biventricular pacing increases cardiac index in patients at risk of left ventricular dysfunction after cardiopulmonary bypass. Procedures included coronary artery bypass, aortic or mitral surgery an...

Ueno, K.I.hi; Togashi, H.; Mori, K.; Matsumoto, M.; Ohashi, S.; Hoshino, A.; Saito, H.; Minami, M.; Yoshioka, M., 2000: The stroke-prone spontaneously hypertensive rat as an animal mode for attention-deficit/hyperactivity disorder. Japanese Journal of Pharmacology 82(Suppl 1): 230P

Pathirana R., 1992: Gamma ray induced field tolerance to phytophthora blight in sesame. Due to the non-availability of sources of resistance in Sri Lanka to Phytophthora blight in sesame (Sesamum indicum) caused by Phytophthora nicotianae var. parasitica, a mutation breeding programme was initiated. Seeds of three genotypes were subj...

Haughton Peter D.W.; McCaffrey William D.; Felix Maarten, 2001: Origin and significance of linked debrites; a key reservoir heterogeneity in sandy turbidite systems. Sediment gravity flow deposits in many extensional/passive margin settings are dominated by a distinctive type of bed couplet comprising (1) a structureless and/or dewatered sandstone bed capped by (2) a heterogeneous mudclast and carbonaceous-cha...

Hausmann, W., 1976: Protective vaccination against anthrax. Praktische Tierarzt: 57 (1) 30

Saxegaard F., 1990: The genus chlamydia and its importance in veterinary and human medicine today. Norsk Veterinaertidsskrift 102(2): 93-102