+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Duplication 8q22.1-q24.1 associated with bipolar disorder and speech delay

, : Duplication 8q22.1-q24.1 associated with bipolar disorder and speech delay. Bipolar Disorders 8(3): 294-298

To report a case of a child with bipolar disorder found to have an unbalanced translocation involving the long arm of chromosome 8, a region that has been previously implicated in genome-wide linkage scans. A 7-year-old boy with a complex psychiatric symptom presentation including attention deficits, distractibility, impulsivity, pressured speech, sleep disturbance, aggressive behavior, and hypersexuality diagnosed with bipolar disorder. He also showed evidence of borderline intellectual and adaptive functioning and had mild dysmorphic features with a duplication of distal 8q that arose as an unbalanced chromosomal translocation due to a maternal 15p;8q insertion. This finding of an unbalanced translocation provides further evidence to support previous linkage studies of a potential causative gene on 8q for bipolar disorder.


PMID: 16696833

DOI: 10.1111/j.1399-5618.2006.00306.x

Other references, C.; Keddy, P.A., 1998: Reserves of buried seeds in beaver ponds. Reserves of buried seeds are known to have an important role in the dynamics of plant communities. This is particularly so in wetlands, where periodic low water events are essential for plants to re-establish from seeds. In spite of the growing li...

Pearsall, A.W.; Cottrell, W.C.; Kovaleski, J., 2001: Leg injury Tennis. Medicine & Science in Sports & Exercise 33(5 Supplement): S93, May

Suzuki T.; Fujishiro Y.; Matsuzaki K.; Miyayama Y.; Kuwaki K., 1968: Long term observation of 4 cases with gastric ulcers case reports. Gastroenterologia Japonica 3(4): 270-271

Muche W.H., 1971: The almost unknown entomological environment of the caucasus. Entomologische Nachrichten 15(6): 53-55

Macedo T.R.A.; Ribeiro C.A.F.; Porfirio M.H.; Cotrim D., 1988: Endothelium dependent relaxing effect of apomorphine in the human uterine artery. British Journal of Pharmacology 95(SUPPL): 719P

Purger, JJ., 1989: New finding of meadow vole, Microtus agrestis (L. 1761) in Vojvodina. Glasnik Prirodnjackog Muzeja I Beogradu Seriya B Bioloske Nauke. 1988- ; 203 Nos 43-44

Efremov, A.E., 1972: Method of obtaining tetraploid Ricinus plants and some of their characteristics. Of 452 seedlings treated with colchicine 134 survived and flowered, two being chimeras and two tetraploids. The tetraploids had large pollen grains, but fertility of the pollen was low as was seed production.

Labonte, P.; Mounir, S., 1996: Expression of HIV unspliced mRNA in a rev-independent manner. Cellular & Molecular Biology (Noisy-Le-Grand) 42(CONGRESS SUPPL ): S73-S74

Romano, F.D.; Naimi, T.S.; Dobson, J.G., 1991: Adenosine attenuation of catecholamine-enhanced contractility of rat heart in vivo. The antiadrenergic action of adenosine was examined in open- and closed-chest preparations of anesthetized rats. The positive inotropic effects of a jugular vein infusion of either isoproterenol or epinephrine were attenuated by phenylisopropylade...

Mees, CC., 1997: Multispecies responses to fishing at Indian Ocean and Tongan offshore reefs. Unknown