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Gene polymorphisms in Uighur patients with Abnormal Savda


, : Gene polymorphisms in Uighur patients with Abnormal Savda. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20(1): 77-78

To investigate gene polymorphisms in Uighur patients with Abnormal Savda. Polymorphisms of genomic fingerprints generated by arbitrarily primed PCR(AP-PCR) can be used for distinguishing between strains of almost any organism. The authors of this article applied the technique to the polymorphism analysis on the DNA of Uighur patients suffering from four kinds of Abnormal Savda (n=116), and on the DNA of a control group(n=50). From the patients, 42 fragments were obtained, among them 27(64.2%) fragments did not show gene polymorphisms. On the 220-344 bp regions, the authors detected 6 AP-PCR products showing individual specificity. The polymorphisms may serve as a molecular marker for gene diagnosis in the patients with Abnormal Savda.

US$29.90

PMID: 12579511


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