geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical Investigation of the Heart Allograft Myocardium (1991-1998)


, : Immunohistochemical Investigation of the Heart Allograft Myocardium (1991-1998). Russian Journal of Immunology 5(1): 33-38

What is a contribution of the humoral (vascular) and mixed type of the rejection episodes to all the episodes of heart allograft rejection is not quite clear, though this factor is of considerable importance for the choice of the treatment methods. The hearts from recipients, as well as endomyocardial biopsies of the heart allografts and postmortem material were investigated with the aim to determine the immunopathological process. Overall, 420 samples from 80 patients were analyzed. Immunofluorescence examination of endomyocardial biopsy showed that in 8 from 44 patients with heart allograft in postoperative period for the first six weeks there were revealed the immunomorphological signs of the acute humoral rejection, manifested as fixation of immunoglobulins and complement in capillaries. Six of them exhibited rejection of mixed type. Most patients in the later postoperative period exhibited a discrete local fixation of immunoglobulins and complement in myocardium, that can be assessed as one of the compartments of the chronic rejection process. In cases of the secondary administration of serum preparations, the fixation of immune complexes was shown in sarcolemma and capillaries, and can be proposed as a sign of serum disease. Repeated acute rejection episodes of humoral or mixed types raised at the first six weeks after transplantation. In the period from 1-5 years after operation, patients displayed discrete deposits of the immunoglobulins and complement as part of the chronic rejection process.

US$29.90

PMID: 12687160


Other references

Ding QiShuo; Ding WeiMin, 2006: Stress wavelets: multi-scale and multi-resolution assessment of soil structure by the drop-shatter method. Stress wavelet properties are inherently involved in the process of the drop-shatter method of assessment on soil structural characteristics. The analogies between wavelet analysis and the drop-shatter process are based on two factors: scale and r...

Ramagopal, S., 1981: Exogenous nucleosides stimulate RNA synthesis in resting cells of a culture of scarlet rose. RNA synthesis in response to exogenous nucleoside precursors was studied in a suspension culture of rose cells. Exponentially growing and resting cells were prelabeled with [3H] uridine, an excess of unlabeled uridine added, and subsequent isotopi...

Snedecor, S.T.; Wilson, H.B., 1949: Some obstetrical injuries to the long bones. Journal of Bone and Joint Surgery. American Volume 31a(2): 378-384

Bendjelid, K., 2008: The pulse oximetry plethysmographic curve revisited. To evaluate the recent literature on the utility of the pulse oximetry plethysmographic curve to assess macrocirculation and microcirculation monitoring in intensive care patients. In patients with sinus rhythm who are hypotensive, deeply sedated,...

Lacey, R.J.; Berrow, N.S.; London, N.J.; Lake, S.P.; James, R.F.; Scarpello, J.H.; Morgan, N.G., 1990: Differential effects of beta-adrenergic agonists on insulin secretion from pancreatic islets isolated from rat and man. The selective beta 2-adrenergic agonist clenbuterol was ineffective as a stimulus for insulin secretion when isolated rat pancreatic islets were incubated with glucose at concentrations between 4 and 20 mM. Inclusion of the phosphodiesterase inhib...

Jain, A.; Shukla, V.Kumar.; Tiwari, V.; Kumar, R., 2008: Antibiotic resistance pattern of group-a beta-hemolytic streptococci isolated from north Indian children. The current resistance pattern of GABHS (group-A beta-hemolytic streptococci) in India has not been discussed. To fill the above-mentioned void, we planned this study to determine the prevalence and degree of antibacterial resistance in GABHS isol...

Leidy R.B.; Sheets T.J.; Nelson L.A., 1986: Residues of fluvalinate and permethrin on flue cured tobacco. High-performance liquid chromatography (HPLC) with C18 reverse-phase columns was used to determine residues of fluvalinate and permethrin applied in the field to flue-cured tobacco in 1980 and 1981. Methods were developed to determine residue leve...

Nikolic, B.; Ljaljevic, J.; Bukilica, M.; Andrejevic, S.; Jovicic, Z.; Dimcic, Z.; Nikolic, M.M.; Janosevic, L.; Arandjelovic, S., 1995: Effect of antineutrophil cytoplasmic autoantibodies on oxidative burst of neutrophils. 9TH INTERNATIONAL CONGRESS OF IMMUNOLOGY [Author] The 9th International Congress of Immunology : 626

Ansanelli, V., 1974: Various aspects of renal function in newborn infants. La Pediatria 82(3): 322-333

Stein, K.B., 1971: Psychotherapy patients as research subjects: problems in cooperativeness, representativeness, and generalizability. Journal of Consulting and Clinical Psychology 37(1): 99-105