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Mechanism and therapy of vascular calcification

, : Mechanism and therapy of vascular calcification. Clinical Calcium 14(5): 752-755

Vascular calcification is clinically important, because it predicts a higher risk of cardiovascular event. Its pathogenesis involve atherosclerosis and regulated by mechanism which like bone metabolism. In dialysis patients, there is excess oxidative stress, shortage of scavenger, metabolic abnormality of calcium and phosphate. These factors may accelerate vascular calcification in dialysis patient. K/DOQI guideline shows the therapeutic strategy for calcium and phosphate metabolic abnormality. It is expected more progression in therapy for vascular calcification.


PMID: 15577037

DOI: CliCa0405752755

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