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New basic science initiatives with the angiotensin II receptor blocker valsartan

, : New basic science initiatives with the angiotensin II receptor blocker valsartan. Journal of the Renin-Angiotensin-Aldosterone System 1(2 Suppl): S3-S5

Angiotensin II (Ang II) plays a key role in the regulation of blood pressure and fluid homeostasis. Valsartan is a highly selective Ang II receptor blocker that specifically and selectively blocks Ang II at the AT1-receptor. In animal models, valsartan has shown positive effects on vasoconstriction, proliferation, remodelling, endothelial function and thrombogenesis, inflammation and atherosclerosis. These data are likely to be confirmed by the results of current clinical trials and valsartan is set to provide improved cardiovascular therapy in the future.


PMID: 17199210

DOI: 10.3317/jraas.2000.052

Other references

Charbonnier, C.; Lädermann, A.; Kevelham, B.; Chagué, S.; Hoffmeyer, P.; Holzer, N., 2017: Shoulder strengthening exercises adapted to specific shoulder pathologies can be selected using new simulation techniques: a pilot study. Shoulder strength training exercises represent a major component of rehabilitation protocols designed for conservative or postsurgical management of shoulder pathologies. Numerous methods are described for exercising each shoulder muscle or muscle...

Puri R.P.; Siddiq E.A., 1980: Inheritance of gelatinization temperature in rice. The present study relates to qualitative genetic characterization of one of the major indices of cooking quality, i.e., gelatinization temperature as measured by KOH degradation. All possible cross combinations of 5 parents were analyzed in F2 and...

Baker C.L.Jr; Baydala A.; Zeitouni N., 1989: Optimal displacement in apparent motion. Measurements are made of the optimal displacement for an abruptly displaced sinewave grating to elicit a motion aftereffect. At a fixed nominal eccentricity of 4 deg, spatial frequencies ranging from 0.2 to 1.2 c/deg are effective in producing an...

Bagheri A.; Johnson L., 1987: Increased degeneration of germ cells late in meiosis and no loss during spermiogenesis in aged men. Journal of Andrology 8(1): P-34

Richard, C.; Monteil, H.; Mégraud, F.; Chatelain, R.; Laurent, B., 1981: Phenotype characteristics of 100 strains of Pseudomonas cepacia. Proposition of a biovars classification. The authors compared the phenotype characteristics of 100 strains of Pseudomonas cepacia mostly of hospital origin to those of the typical mother strain (ATCC 25416). The morphological, cultural and biochemical characteristics (oxidase characteris...

Kathirithamby, J.; Johnston, J.Spencer., 2004: The discovery after 94 years of the elusive female of a myrmecolacid (Strepsiptera), and the cryptic species of Caenocholax fenyesi Pierce sensu lato. Due to its extreme sexual dimorphism and disparate hosts, no female myrmecolacid has been matched to its conspecific male to date. Here, for the first time to our knowledge, a morphological description is given of the matched female and male myrme...

Koizumi, T.; Nakagawa, M.; Nagamatsu, S.; Kayano, S.; Akazawa, S.; Katsuragi, Y.; Matsui, T.; Yamamoto, Y., 2014: The versatile perifascial areolar tissue graft: adaptability to a variety of defects. Reconstruction using flaps with good blood circulation is appropriate for covering an intractable ulcer or a fistula in which tendon or bones are exposed. A non-vascularised perifascial areolar tissue (PAT) graft can also survive in such an area....

Ashar, M.N.; Prajapati, J.B., 2000: Effect of feeding Lactobacillus acidophilus V3 on the lipemic status of humans of different age groups. The effect of a probiotic strain, Lactobacillus acidophilus V3, a human vaginal isolate, was studied on the lipaemic status of 27 human subjects of varying age groups, namely, 20-40 years (A1), 40-60 years (A2) and 60-80 years (A3) Anand, Gujarat,...

Gellis, S.S.; Feingold, M., 1974: Oculodentodigital dysplasia. Picture of the month. American Journal of Diseases of Children 128(1): 81-82

Mcdermott, M.R.; Brook, M.A.; Heritage, P.L.; Underdown, B.J.; Loomes, L.M.; Jiang, J., 1996: Microparticle delivery system with a functionalized silicone bonded to the matrix. Official Gazette of the United States Patent & Trademark Office Patents 1192(1): 369, Nov 5