geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Quality of life and symptom control in hospice patients with cancer receiving chemotherapy


, : Quality of life and symptom control in hospice patients with cancer receiving chemotherapy. Journal of Palliative Medicine 9(3): 638-645

The value of palliative chemotherapy for hospice patients is difficult to quantify and little is known about outcomes from these treatments. This study examined quality of life and symptom control in hospice patients with cancer receiving chemotherapy and in a control group of hospice patients with cancer who had not received chemotherapy for at least 3 months. Using a case-control study design matching patients by age, gender, race, and cancer diagnosis, patients receiving chemotherapy reported a similar number of symptoms as patients off chemotherapy. Global symptom distress was comparable in both groups as was quality of life. Patients in both groups were similar at the symptom-specific level, however, patients on chemotherapy had better symptom outcomes for urination problems (p=0.03), numbness/tingling (p=0.03), muscle weakness (p=0.07), and pain (p=0.09). Patients on chemotherapy had poorer symptom control involving change in taste (p=0.01) and cough (p=0.01). Patients on chemotherapy were more likely than those off chemotherapy to report that chemotherapy "made them feel better" (p=0.01) and "allowed better symptom control" (p=0.01), indicating that patients taking chemotherapy had more subjective benefit from chemotherapy when compared to those off chemotherapy. The two groups showed no difference in the rate of survival.

US$19.90

PMID: 16752969

DOI: 10.1089/jpm.2006.9.638


Other references

Kueh, J.; Richards, M.; Ng, S-Wai.; Chan, W-Khiong.; Bongso, A., 2006: The search for factors in human feeders that support the derivation and propagation of human embryonic stem cells: preliminary studies using transcriptome profiling by serial analysis of gene expression. Serial analysis of gene expression (SAGE) was used to obtain the transcriptome profiles of a supportive human fetal skin feeder (Detroit 551) and a nonsupportive human fetal lung feeder (MRC-5) for human embryonic stem cells. A pairwise comparison...

Falit, B.P.; Singh, S.C.; Brennan, T.A., 2015: Biosimilar competition in the United States: statutory incentives, payers, and pharmacy benefit managers. Widespread adoption of generic medications, made possible by the Hatch-Waxman Act of 1984, has contained the cost of small-molecule drugs in the United States. Biologics, however, have yet to face competition from follow-on products and represent...

Hillman, M., 1997: Cyclists should wear helmets. Health benefits of cycling greatly outweigh loss of life years from deaths. Bmj 314(7073): 70-70

Bracali, G., 1954: Morphological picture of the hypothalamus in malignant neoplasia. Archivio Italiano di Anatomia E Istologia Patologica 27(1-2): 50-105

Alam, Sm, 1981: Effects of solution pH on the growth and chemical composition of rice plants Oryza sativa, nutrient solution. Journal of plant nutrition(3): 247-260

Berendonk, T.U., 2002: Distribution and ecology of phantom midge larvae in southern France and Italy (Diptera: Chaoboridae). A survey for Chaoborus was conducted in 2000 and 2001 in Southern France and Italy. Larvae of C. obscuripes (VAN DER WULP) are recorded for the first time in France. Four specil were recorded raising the number of Chaoborus species known from sout...

Vernooij, M.; Claessens, T.; Luijten, M.; van Steensel, M.A.M.; Coull, B.J., 2014: Birt-Hogg-Dubé syndrome and the skin. Birt-Hogg-Dubé syndrome (MIM #135150) is characterized by the development of benign skin tumours called fibrofolliculomas, pulmonary cysts that may lead to pneumothorax and a high risk of developing kidney cancer. BHD is caused by mutations affec...

Farah, G.; Petit-Boulanger, C.; Hewson, D.J.; Duchêne, J., 2006: Surface electromyography as a tool to assess the responses of car passengers to lateral accelerations. Part II: Objective comparison of vehicles. The purpose of this study was to objectively assess the response of car passengers to lateral accelerations. Surface EMG signals were collected bilaterally from the cervical erector spinae (CES), latissimus dorsi (LD), erector spinae (ES), externa...

Mashima, H.; Shibata, H.; Mine, T.; Kojima, I., 1996: Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor. Pancreatic AR42J cells are derived from acinar cells and express both exocrine and neuroendocrine properties. We have recently shown that these cells convert into insulin-producing cells in vitro after treatment with activin A and betacellulin. He...

Islam, R.; Rahman, S.M.; Hossain, M.; Joarder, O.I., 1993: In vitro clonal propagation of papaya (Carica papaya L.). A protocol was developed for the rapid clonal propagation of pawpaw (cv. Rajshahi-red) using apices dissected from mature, field-grown plants. The apices were cultured on MS medium supplemented with kinetin (5, 10 and 15 mg/litre) plus NAA (0.5, 1...