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Safety and efficacy of percutaneous neuromodulation therapy in the management of subacute radiating low back pain

, : Safety and efficacy of percutaneous neuromodulation therapy in the management of subacute radiating low back pain. Pain Practice 3(2): 125-134

Percutaneous neuromodulation therapy (PNT) is a new minimally invasive, office-based treatment for low back pain in which electrical stimulation is delivered to the paraspinal peripheral nerves. The purpose of this study was to determine the safety, tolerability, and clinical efficacy of PNT in a population of patients with subacute low back pain with radiation to the lower extremity. Open label prospective clinical trial. Multi-center outpatient setting. We enrolled 83 patients who had radiating low back pain for 4 weeks to 6 months with a pain intensity of at least 4 on a visual analog scale of 0-10. Subjects were treated with PNT 1 to 2 times per week for at least 4 weeks. Based on clinical response patients were treated up to an additional 8 weeks. We recorded baseline visual analog scale (VAS) scores of radiating pain, low back pain, physical activity, and sleep, as well as the Oswestry Disability Questionnaire. Follow-up assessments were performed at each session, and at 5 and 12 weeks. Patients benefiting from treatments at 12 weeks were followed-up at 6 months. Fifty-nine patients completed the study protocol. Mean VAS scores improved as follows: leg/buttock pain decreased by 37% to 4.0 +/- 2.6 from a baseline of 6.6 +/- 1.7 (P < 0.001); low back pain decreased by 26% to 3.9 +/- 2.4 from a baseline of 5.5 +/- 2.2 (P < 0.001); activity levels improved by 38% to 3.6 +/- 2.2 from a baseline of 6.0 +/- 2.2 (P < 0.001); and sleep improved by 27% to 3.1 +/- 2.5 from a baseline of 4.8 +/- 3.0 (P < 0.001). The Oswestry Low Back Pain Disability scores improved by 24% to 32 +/- 16 from a baseline of 43 +/- 15 (P < 0.001). Pain relief was sustained over a 3-month observation period. For many patients with subacute radiating low back pain, PNT significantly reduced pain and self-rated disability, and improved sleep quality and activity level. PNT is safe and generally well tolerated.


PMID: 17163911

DOI: 10.1046/j.1533-2500.2003.03019.x

Other references

Torrealba, J.F.; Pieter, O.Io.G.; Guerr, M.Ra.E., 1954: A case of brucellosis treated with ilotycin. Gaceta Medica de Caracas 61(3-5): 111-115

Kolievskaya-Yu, A.; Ivanyuk, E.G., 1975: Determination of isomers of nitrochloro benzene in air of industrial rooms by gas chromatography. A gas-chromatographic method is described for determining ortho-, meta- and para-nitrochlorobenzene, used in the production of dyes, present together in the air of industrial rooms. The sensitivity of the method is 1 mg/m3, and the time of analysi...

Perry, I.J.; Gosling, P.; Sanghera, K.; Churchill, D.; Luesley, D.M.; Beevers, D.G., 1993: Urinary microalbumin excretion in early pregnancy and gestational age at delivery. Bmj 307(6901): 420-421

Caminas, Juan A., 1996: Loggerhead Caretta caretta Linnaeus, 1758 sightings and strandings in the Alboran sea and adyacent areas during 1979-1994 Avistamientos y varamientos de tortuga boba Caretta caretta Linnaeus, 1758 en el mar de Alboran y areas adyacentes durante el periodo 1979-1994. Revista Espanola de Herpetologia, 10: 109-116

Merkel, I.S.; Rabinovitz, M.; Dekker, A., 1992: Cecal inflammatory fibroid polyp presenting with chronic diarrhea. A case report and review of the literature. Digestive Diseases and Sciences 37(1): 133-136

Gambassi, G., 1974: Drug therapy of gastro-duodenal ulcer. La Clinica Terapeutica 71(4): 301-312

Zaitzev, A.V., 1955: The annual cycle of testes in pike. CR Acad Sci URSS: 101: 185-187

Chzhen, O., 1954: Inhibition of cell division in the corneal epithelium by conditioned stimuli. Doklady Akademii Nauk SSSR 99(6): 1111-1114

Wetter, D.A.; Camilleri, M.J., 2010: Clinical, etiologic, and histopathologic features of Stevens-Johnson syndrome during an 8-year period at Mayo Clinic. To examine clinical, etiologic, and histologic features of Stevens-Johnson syndrome and to identify possible correlates of clinical disease severity related to etiologic and histopathologic findings. This is a retrospective review of patients seen...

Richardson Stephen H.; Shirey Steven B.; Harris Jeffrey W., 2004: Episodic diamond genesis at Jwaneng, Botswana, and implications for Kaapvaal Craton evolution. Major element and Re-Os isotope analysis of single sulfide inclusions in diamonds from the 240 Ma Jwaneng kimberlite has revealed the presence of at least two generations of eclogitic diamonds at this locality, one Proterozoic (ca. 1.5 Ga) and the...