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Sequence characterization, tissue-specific expression and polymorphism of the porcine (Sus scrofa) liver-type fatty acid binding protein gene

, : Sequence characterization, tissue-specific expression and polymorphism of the porcine (Sus scrofa) liver-type fatty acid binding protein gene. Yi Chuan Xue Bao 33(7): 598-606

In this study, the full-length cDNA of porcine liver-type fatty acid binding protein gene (L-FABP) was obtained by the rapid amplification of cDNA ends (RACE). The nucleotide sequence and the predicted protein sequence share a high sequence identity with their mammalian counterparts. Semi-quantitative RT-PCR revealed that porcine L-FABP gene is expressed in all twelve tissues studied, but a transcript is more abundant in liver and small intestine than in other tissues. The part genomic DNA of the porcine L-FABP gene was amplified by PCR. The coding region of the pig L-FABP gene is organized in four exons and spans an approximate 2.62 kb genomic region. Comparative sequencing of four pig breeds revealed a C-->T single nucleotide polymorphism (SNP) within exon 2. The allele and genotype frequencies differed significantly between indigenous Chinese Zang, Dahe, and Yanan pigs with higher frequencies of allele C and genotype CC and Yorkshire pigs with higher frequencies of allele T and genotype TT (P < 0.01). The association analysis suggested that the C-->T polymorphism was associated with intramuscular fat content, indicating that the SNP is a potential molecular marker for intramuscular fat content.


PMID: 16875317

DOI: 10.1016/S0379-4172(06)60089-9

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Isely, R.B.; Mvele, P.; Rao, V., 1982: Evaluation of the prognosis of a village health community in the Cameroon: results of an economic and attitude study. Annales de la Societe Belge de Medecine Tropicale 62(2): 157-168

Bertrand, D.; Wolf, A.D., 1959: The need of Aspergillus niger for the trace element zinc in the synthesis of tryptophane, and its possible substitution by cadmium.. Unlike Neurospora crassa, A. niger does not possess the enzyme required for the synthesis of tryptophane. While cultures of A. niger contained insignificant amounts of tryptophane if grown in presence of 10-25 micro g// Zn, the concentration of th...

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