+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Surgical approach to tumor recurrence and metastatic lesions of the liver in a patient with malignant endocrine tumors of the pancreas: case report

, : Surgical approach to tumor recurrence and metastatic lesions of the liver in a patient with malignant endocrine tumors of the pancreas: case report. Journal of Hepato-Biliary-Pancreatic Surgery 10(4): 325-328

We describe herein a 72-year-old woman with tumor recurrence in the residual pancreas and metastasis to the liver following a pylorus-preserving pancreatoduodenectomy for multiple endocrine tumors in the head of the pancreas. Abdominal ultrasonography performed 7 years after the initial surgery detected new lesions in the residual pancreas and liver. After recurrence of endocrine tumors of the pancreas and metastasis to the liver were diagnosed, the lesions were successfully resected by total pancreatectomy with distal gastrectomy and both lateral segmentectomy and partial resection of segment 8. Genetic analysis using a blood specimen showed that this patient carried the multiple endocrine neoplasia type 1 (MEN1) gene mutation. One year after the second resection, the patient remains in good health using insulin and has not shown any sign of recurrence. This case report describes successful surgical resection for recurrence and metastasis of malignant endocrine tumors in a patient with the MEN1 gene mutation.


PMID: 14598155

DOI: 10.1007/s00534-002-0861-0

Other references

Cohn, Jeffrey P., 1989: Gauging the biological impacts of the greenhouse effect. The World Wildlife Fund recently sponsored a conference on the biological consequences of the greenhouse effect, which climatologists believe could raise average global temperatures 3[degree] to 5[degree] C within the next century. The researchers...

Genchev, G., 1974: Hereditary plant tumors and the genetic conception of cancer. Voprosy Onkologii 20(4): 79-83

Bang, N.Duc.; Caws, M.; Truc, T.Thanh.; Duong, T.Ngoc.; Dung, N.Huy.; Ha, D.Thi.Minh.; Thwaites, G.E.; Heemskerk, D.; Tarning, J.; Merson, L.; Van Toi, P.; Farrar, J.J.; Wolbers, M.; Pouplin, T.; Day, J.N., 2016: Clinical presentations, diagnosis, mortality and prognostic markers of tuberculous meningitis in Vietnamese children: a prospective descriptive study. Tuberculous meningitis in adults is well characterized in Vietnam, but there are no data on the disease in children. We present a prospective descriptive study of Vietnamese children with TBM to define the presentation, course and characteristics...

D.B.rnardez Clark, E.; Schwarz, E.; Rudolph, R., 1999: Inhibition of aggregation side reactions during in vitro protein folding. Methods in Enzymology 309: 217-236

Crespi, M., 1962: Considerations On Osteogenesis Imperfecta. Archivio di Ortopedia 75: 1356-1361

Harrison, R.V., 1984: Objective measures of cochlear frequency selectivity in animals and in man. A review. This paper is based on a review lecture presented at the Scientific Workshop on Evoked Potentials at Brugmann University Hospital, Brussels, Belgium on 25 February, 1984. The first part briefly reviews electrophysiological studies in experimental...

Ammon, H.P.T.; Kelber, O.; Okpanyi, S.N., 2000: Spasmolytic and tonic effect of Iberogast R STW 5 in intestinal smooth muscle. STW 5 (Iberogast (R)) is a fixed combination of nine medicinal plant extracts effective in the treatment of functional dyspepsia and irritable bowel syndrome. The effects of STW 5, a combination of Iberis amara fresh plant extract, and other eigh...

Schäfer, N.; Yu, Z.; Wagener, A.; Millrose, M.K.; Reissmann, M.; Bortfeldt, R.; Dieterich, C.; Adamski, J.; Wang-Sattler, R.; Illig, T.; Brockmann, G.A., 2014: Changes in metabolite profiles caused by genetically determined obesity in mice. The Berlin Fat Mouse Inbred (BFMI) line harbors a major recessive gene defect on chromosome 3 (<i>jobes1</i>) leading to juvenile obesity and metabolic syndrome. The present study aimed at the identification of metabolites that might b...

Wasir, H.S., 1995: Need for national hypertension control programme. Indian Heart Journal 47(4): 409-410

Hartsfield, Sm, 1971: The economics of herd health management. Southwestern veterinarian: er 24 (4) 307-309