geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Touch and go: guidance cues signal to the growth cone cytoskeleton


, : Touch and go: guidance cues signal to the growth cone cytoskeleton. Current Opinion in Neurobiology 15(5): 521-526

Growth cones, the highly motile tips of growing axons, guide axons to their targets by responding to molecular cues. Growth cone behaviors such as advancing, retracting, turning and branching are driven by the dynamics and reorganization of the actin and microtubule cytoskeleton through signaling pathways linked to guidance cue receptors. Actin filaments play a major part in growth cone motility, and because of their peripheral locations were thought to be the primary target of molecular cues. However, recent studies have shown that dynamic microtubules can penetrate the growth cone periphery where guidance molecules can influence them directly. Moreover, guidance cues can regulate growth cone steering by modulating dynamic actin-microtubule interactions.

US$19.90

PMID: 16143510

DOI: 10.1016/j.conb.2005.08.005


Other references

He, H.; Stark, M.; Fleming, D.; Weir, B.; Gould, J., 1996: The effects of HIV counseling and testing among out-of-treatment injection drug and crack users. ELEVENTH INTERNATIONAL CONFERENCE ON AIDS [Author] Eleventh International Conference on AIDS, Vol Two One world: One hope : 153-154

Gramling, L.F.; Lambert, V.A.; Pursley-Crotteau, S., 1998: Coping in young women: theoretical retroduction. Although there is increasing interest in women's health, there remains little empirical evidence concerning concepts related to health and women's life trajectory. Our purpose in conducting this research was to examine women's devel...

Chiasson, D.; Ekengren, S.K.; Martin, G.B.; Dobney, S.L.; Snedden, W.A., 2005: Calmodulin-like proteins from Arabidopsis and tomato are involved in host defense against Pseudomonas syringae pv. tomato. Complex signal transduction pathways underlie the myriad plant responses to attack by pathogens. Ca2+ is a universal second messenger in eukaryotes that modulates various signal transduction pathways through stimulus-specific changes in its intrac...

Ogeturk, M.; Kose, E.; Sarsilmaz, M.; Akpinar, B.; Kus, I.; Meydan, S., 2011: Effects of lemon essential oil aroma on the learning behaviors of rats. Neurosciences 15(4): 292-293

Carminatti, G.; Javelot, S., 1992: Confrontation over farming at GATT. Since the opening of the Uruguay Round of GATT talks in 1986, agricultural trade has dominated, and blocked talks especially between the EC and the USA. All countries agree on the need for reform, and for security of food supply. However the USA i...

Iskandar, A.; Sihombing, U.; Sudrajat, P.; Santosa, A.; Triyadi, A.; Djabar, S., 1984: The development of teaching strategies for post-literacy and the continuing education of neo-literates within the context of permanent education in Indonesia. The results of an international research project of the Unesco Institute for Education in collaboration with the German Commission for Unesco, Bonn. The study describes the general educational situation in Indonesia, and then focuses on PENMAS, the community education division of the Ministry of Education and Culture. PENMAS aims to provide basic education for illiterates, or people who droppe...

Becker M.A.; Yen R.C.K.; Goss S.; Seegmiller J.E.; Itkin P.; Lazar C.; Adams W.B., 1978: Localization of the structural gene for human phospho ribosyl pyro phosphate synthetase on the x chromosome. Clinical Research 26(2): 114A

Xie, K.; Yang, S.; Zhu, Y.M., 2011: 3D visualization and simulation in surgical planning system of orbital hypertelorism. Simulation and three-dimensional visualization of object motion is a prerequisite for any surgical planning system. Orbital hypertelorism is a disease, which is most commonly associated with craniofacial malformations. We have developed a surgical...

Neumark, Y.D.; Lopez-Quintero, C.; Grinshpoon, A.; Levinson, D., 2007: Alcohol drinking patterns and prevalence of alcohol-abuse and dependence in the Israel National Health Survey. Coexistence of disparate religious/cultural mores with regard to alcohol drinking within the changing social milieu of Israel provides an informative environment for investigation of alcohol consumption patterns and alcohol-related mental disorder...

Flores-Cantu, H.; Camara-Lemarroy, C.R.; Calderon-Hernandez, H.J.; Zapata-Rivera, M.A.; Villareal-Perez, J.Z.; Villareal-Velazquez, H.J., 2016: Anti-GAD Antibody, Seizures, Cerebellar Ataxias and Vitiligo: A Diagnostic Challenge. Cerebellum 14(3): 375-377