+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Transcription and translation of Dickkopf-1 in endometrium of pregnant mice during the peri-implantation period

, : Transcription and translation of Dickkopf-1 in endometrium of pregnant mice during the peri-implantation period. Journal of Huazhong University of Science and Technology. Medical Sciences 24(6): 625-7, 638

To study the expression of Dickkopf-1 (DKK-1) in endometrium of pregnant mice during the peri-implantation period and the role of DKK-1 during the embryo implantation in mice. Immunohistochemical technique was employed to determine the location of DKK-1 protein in endometrium, and semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR) was utilized to determine the levels of DKK-1 mRNA. Our results showed that the expressions of DKK1 mRNA and protein were higher in experimental groups than in control group (P<0.01) and it increased significantly on day 3 and reached its peak on day 4, and then decreased gradually on day 5-7. The levels of DKK-1 mRNA and protein on day 4 was significantly higher than those of other groups (P<0.01). It is concluded that DKK-1 probably plays an important role in signal transudation of embryo implantation and its high expression indicates the opening of implantation window.


PMID: 15791861

Other references

Martos D.E.; Peralta E.H., 1983: Geochemical map of the Catamarca Province. 2: 537-549 1983

Liss, G.M.; Stock, S.R., 1996: Can Dupuytren's contracture be work-related?: review of the evidence. Dupuytren's contracture (DC) is a disease of the palmar fascia resulting in thickening and contracture of fibrous bands on the palmar surface of the hands and fingers. For decades, a controversy has existed regarding whether acute traumatic i...

Chentsov, Y.S.; Burakov, V.V.; Kosykh, M.I., 2000: Nuclear matrix proteins are carried within peripheral material of mitotic chromosomes. Immunofluorescent analysis has shown that autoimmune sera M-222 and M-260 are bound to interphase nuclei and mitotic chromosomes of the pig embryo kidney cell culture. The fluorescent stain is diffuse in nuclei and forms a thin fluorescent area ar...

Ferdinandusse, S.; Ylianttila, M.S.; Gloerich, J.; Koski, M.Kristian.; Oostheim, W.; Waterham, H.R.; Hiltunen, J.Kalervo.; Wanders, R.J.A.; Glumoff, T., 2005: Mutational spectrum of D-bifunctional protein deficiency and structure-based genotype-phenotype analysis. D-bifunctional protein (DBP) deficiency is an autosomal recessive inborn error of peroxisomal fatty acid oxidation. The clinical presentation of DBP deficiency is usually very severe, but a few patients with a relatively mild presentation have bee...

Uddin, M.Shams.; Bhugra, D.; Johnson, M.R.D., 2008: Perceptions of drug use within a UK Bengali community. The study set out to explore the perceptions and knowledge of drug use of the Bangladeshi origin population in Leicester through local Mosques and community and resource centers for recruiting subjects. A triangulated methodology was used for this...

Alm P.; Asking B.; Emmelin N.; Gjorstrup P., 1984: Innervation of the rat parotid gland from the contralateral cervical sympathetic trunk. Acta Physiologica Scandinavica 121(3): 6A

Davis, R.T., 1957: Linear position preference habits of monkeys. Journal of Genetic Psychology 91(2): 233-238

Lee, Sang Jun, 2001: Heating pot for decocting chinese herbs. A heating pot for decocting Chinese herbs, including a container on which Chinese herbs are to be contained, a heater received in the container so as not to contact the container, and a condenser installed on the opening of the container, for cond...

Zinsou, C.; Desfontaines, L.; Sobesky, O., 1998: Chemical and biochemical composition of tubers of Apios americana Medikus grown ex situ. Apios americana is a new nitrogen-fixing crop that produces seeds and tubers, native to eastern North America. Grown in Guadeloupe, out of its usual waterlogged habitat, it produced tubers, which were analysed for chemical and biochemical composit...

Montgomery, W.H.; Wahl, M.; Hettrich, C.; Itoi, E.; Lippitt, S.B.; Matsen, F.A., 2005: Anteroinferior bone-grafting can restore stability in osseous glenoid defects. Glenohumeral instability associated with a large osseous defect of the glenoid can be treated with bone graft to restore the glenoid concavity. The shape and positioning of the graft is critical: a graft that encroaches on the extrapolated glenoid...