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A case series of lamotrigine increased to 300mg daily in patients with bipolar depression

, : A case series of lamotrigine increased to 300mg daily in patients with bipolar depression. Asian Journal of Psychiatry 4(3): 223-223

Bipolar depression is a condition lacking sufficient treatment options. While lamotrigine appears effective, clinical trials and prescribing guidelines address only daily doses below 300mg. Thirteen consecutive outpatients with bipolar depression and taking 200mg of daily lamotrigine were openly administered a dose increased to 300mg and naturalistically followed. Study outcome was assessed by comparison of pre- and post-treatment Beck Depression Inventory (BDI) and Global Assessment of Functioning (GAF) scores. Stastical analysis applied the paired t-test. Increasing daily lamotrigine dose to 300mg was associated with good tolerability and significant improvement in BDI and GAF scores.


PMID: 23051124

DOI: 10.1016/j.ajp.2011.05.007

Other references

Winjum, J.K.; Dixon, R.C.; Schroeder, P.E., 1997: Carbon storage in forest plantations and their wood products. The potential for forestation practices on a global scale to store carbon on site and in durable wood products after harvest is evaluated in the context of recent projections on climatic change. Mean Carbon Storage (MCS) in above- and below-ground...

Jesus, L.E.; Dekermacher, S.; Frota, Júlia.; Bragança, J.J.; Anderson, K.M., 2015: Adolescents and adults in pediatric urology clinics. Adolescents represent a significant proportion of the patients seen by pediatric urologists (PU). Adolescents that require long-term follow-up (FU) eventually need to be transferred to adult care. This research aims to describe the disease profile...

Mai S.; Yates R.; Ramos L.; Del Tito B.; Oka M., 1987: Inactivation and degradation of tissue type plasminogen activator in recombinant chinese hamster ovary cell cho suspension culture. Abstracts of Papers American Chemical Society 194: MBTD 169

Preobrazhenskaya E.S.; Kriviskii A.S., 1980: Necessity of de novo protein synthesis for realization of uv induced mutations of virulent bacterio phage s d. Soviet Genetics (English Translation of Genetika) 16(12): 1349-1358

Brzezinska Paudyn A.; Van Loon J.C.; Balicki M.R., 1986: Multielement analysis and mercury speciation in atmospheric samples from the toronto area canada. Inductively coupled plasma atomic emission spectrometry (ICP-AES), graphite furnace atomic absorption (GFAAS) and gas chromatography with an atomic absorption detector (GC-AAS) were used for the analysis of atmospheric samples collected in the Tor...

Cheng, S.L.; Chen, Y.; Crang, R.F.E.; Yeager, M.; Domier, L.L.; D'arcy, C.J., 1995: Imaging of barley yellow dwarf virus by cryo-transmission electron microscopy and high resolution cryo-scanning electron microscopy. Phytopathology 85(10): 1209

Margot Scholte, Ard Sprinkhuizen, 2010: Sobere oplossingen bij complexe problemen. De Wmo is een exemplarisch voorbeeld van het nieuwe denken waarbij de eigen verantwoordelijkheid van mensen en zorg voor elkaar (meedoen!) centraal staan. Dit vraagt om een nieuw evenwicht in de hulp- en dienstverlening. Werken aan versterking van...

Besemer, K., 2016: Biodiversity, community structure and function of biofilms in stream ecosystems. Multi-species, surface-attached biofilms often dominate microbial life in streams and rivers, where they contribute substantially to biogeochemical processes. The microbial diversity of natural biofilms is huge, and may have important implications...

Gangde, C.N.; Patil, N.E.; Madansure, V.N.; Chaudhary, A.A., 1998: Characterization of biomass fuels for gasification. Physical properties, proximate analysis and heating values of Babool (Acacia nilotica) wood without bark, Subabool (Leucaena leucocephala) round wood with bark, Safflower (Carthamus tinctorius) residues briquette and Tur (Cajanus cajan) stalks wer...

Dutkiewicz, J.S., 1955: Modifications of body weight and of body temperature in man following exposure to high environmental temperature; effect of dry heat. Acta Physiologica Polonica 6(4): 377-385