geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A central role for long non-coding RNA in cancer


, : A central role for long non-coding RNA in cancer. Frontiers in Genetics 3: 17-17

Long non-coding RNAs (ncRNAs) have been shown to regulate important biological processes that support normal cellular functions. Aberrant regulation of these essential functions can promote tumor development. In this review, we underscore the importance of the regulatory role played by this distinct class of ncRNAs in cancer-associated pathways that govern mechanisms such as cell growth, invasion, and metastasis. We also highlight the possibility of using these unique RNAs as diagnostic and prognostic biomarkers in malignancies.

US$19.90

PMID: 22363342

DOI: 10.3389/fgene.2012.00017


Other references

Braselmann H.; Meyer R., 1986: Post mortem ion analysis in myocardium of children after surgery for malformation. Commonly, children dying after operation on congenital cardiac malformation, show only minor histological changes in the myocardium. We have attempted to correlate the myocardial ion (Na+,K+, Ca2+) composition with the probable severity of hypoxia...

Takahashi, H.; Waggoner, S.E.; Boyd, J., 1995: Molecular genetic analysis of diethylstilbestrol -associated clear-cell carcinomas of the vagina and cervix. Gynecologic Oncology 56(1): 137

Georgopoulos, A.P., 2012: The Minnesota Women Healthy Aging Project. The Minnesota Women Healthy Aging Project is an effort to understand how the brain changes with age and why some brains are more resilient than others. Using a unique methodology, researchers are evaluating the brain status of a number of women by...

Stoeck, T.; Welter, H.; Seitz Bender, D.; Kusch, J.; Schmidt, H.J., 2000: ARDRA and RAPD-fingerprinting reject the sibling species concept for the ciliate Paramecium caudatum. Morphologically indistinguishable sibling species also known as syngens are a characteristic taxonomic feature of the ciliate genus Paramecium. This has been convincingly demonstrated for the P. aurelia species complex. For a long time this featur...

Bale, A.J.; Morris, A.W., 1981: Laboratory simulation of chemical processes induced by estuarine mixing; the behaviour of iron and phosphate in estuaries. Estuarine, Coastal and Shelf Science 13(1): 1-10

Anderssen, V., 1981: Quality evaluation of accommodation milk. The Finnish legislation on accommodation milk (milk delivered to dairies from milk reception stations or from other dairies) is explained. Decree No. 453/75 of the Ministry of Agriculture and Forestry lays down procedures for sampling and testing...

Wright, A.F., 1999: Through a glass darkly: understanding depression. British Journal of General Practice 49(439): 91-92

Rensburgh, H.J.V.n Strijdom, B.W.; Rabie, C.J., 1968: Nature of the genetic determinant of effectiveness in strains of Rhizobium japonicum. Of 13 strains of Rh. japonicwn exposed to ultraviolet irradiation and also cultured on a yeast mannitol broth supplemented with acrifiavine, several failed to nodulate after inoculation in soya-bean plants. Results suggest the presence of a cytopl...

Toyoda, J.; Hisayama, T.; Takayanagi, I., 1987: Effects of nitro compounds, isosorbide dinitrate, 5-isosorbide mononitrate and glyceryl trinitrate on Ca-uptake into Ca-stores and Ca-release from Ca-stores in rabbit isolated femoral veins and femoral arteries. In organ bath studies, effects of isosorbide dinitrate (ISDN), 5-isosorbide mononitrate (ISMN), a major metabolite of ISDN, and glyceryl trinitrate (GTN) on Ca-uptake into Ca-stores and Ca-release from Ca-stores were tested in the rabbit isolated...

Pras, E.; Wouda, J.; Willemse, P.H.B.; Midden, M.E.; Zwart, M.; de Vries, E.G.E.; Schultz, W.C.M.Weijmar., 2003: Pilot study of vaginal plethysmography in women treated with radiotherapy for gynecological cancer. Objectives. After pelvic radiotherapy for gynecological cancer, changes in the vaginal epithelium might influence sexual arousal and satisfaction, leading to dyspareunia and relational problems. The aim of the study was to determine the feasibilit...