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A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore


, : A prospective comparison of chronic primary angle-closure glaucoma versus primary open-angle glaucoma in Singapore. Singapore Medical Journal 54(3): 140-145

To describe the optic disc, visual field and ocular characteristics of a consecutive cohort of Asian patients with chronic primary angle-closure glaucoma (CPACG), and compare them with those having primary open-angle glaucoma (POAG). In a prospective comparative case series of new patients with POAG or CPACG in Singapore, all patients underwent visual acuity assessment, slit-lamp examination, tonometry, gonioscopy, refraction, Heidelberg Retina Tomograph (HRT) and Humphrey visual field (HVF) assessment. 98 patients were enrolled (POAG n = 48; CPACG n = 50). CPACG patients were significantly older (66.5 ± 9.2 years vs. 64.1 ± 13.5 years; p = 0.027) and mostly female (p = 0.004). CPACG eyes had significantly higher intraocular pressure (26.9 ± 6.9 mmHg vs. 24.5 ± 3.3 mmHg; p = 0.03), shorter axial length (22.89 ± 0.97 mm vs. 24.26 ± 1.79 mm; p < 0.001) and shallower anterior chamber depth (2.60 ± 0.25 mm vs. 3.16 ± 0.48 mm; p < 0.001). HVF mean deviation or pattern standard deviation (PSD) did not differ significantly between POAG and CPACG eyes, but the latter had a lower PSD for a given mean deviation. HRT parameters between the two groups were not significantly different. In this study, CPACG eyes had significantly higher presenting intraocular pressure than POAG eyes, but there were no significant differences in optic disc topography. A majority of the patients in both groups had moderate field defects at the time of presentation, followed by severe and then mild defects. The field loss in CPACG eyes was more diffuse than that in POAG eyes.

US$29.90

PMID: 23546026


Other references

Abe, K.; Esaki, H.; Ryu, N.; Esaki, N., 1969: Hygienic studies on instant rah mein. II. A quantitative analysis of the salt in instant rah mein. Kurume Medical Journal 16(1): 25-31

Shevchenko G.M., 1972: Effect of the posterior root reflexes on impulses entering the spinal cord. Byulleten' Eksperimental'noi Biologii i Meditsiny 74(8): 3-6

Grant, D.L., 1976: Oil and gas leasing of Idaho farm and ranch land. This bulletin discusses the legal rights and duties of a farmer or rancher who enters into an oil and gas lease assuming that the farmer owns both the surface and the mineral rights at the time of leasing. The discussion is on general principles w...

Bordley, J.E.; Haskins, H.L., 1955: The role of the cerebrum in hearing. Annals of Otology, Rhinology, and Laryngology 64(2): 370-382

Mast, A.E.; Broze, G.J., 1996: Physiological concentrations of tissue factor pathway inhibitor do not inhibit prothrombinase. Tissue factor pathway inhibitor (TFPI) is a Kunitz-type serine proteinase inhibitor that directly inhibits factor Xa and, in a factor Xa dependent manner, inhibits the factor VIIa/tissue factor catalytic complex. The inhibitory effect of TFPI in p...

Feliciano, D.V., 2001: Management of penetrating injuries to carotid artery. The diagnosis and management of penetrating injuries to the cervical carotid arteries continue to be controversial. Most patients with stab or gunshot wounds to the common or internal carotid artery in cervical zone II (sternal notch to angle of m...

Edmunds, J., 1981: Pholcus phalangioides (Fuesslin) in Lancashire. British Arachnological Society Newsletter, 10-11 No. 30

Balaban, N.; Goldkorn, T., 2004: Target of RNAIII activating protein. The present invention is directed to a protein isolated from S. aureus that is the target of RAP, called TRAP, which is characterized by a molecular weight of about 21 KDa, is capable of being phosphorylated by RAP, and comprises an amino acid seq...

M.Hashemi, M.R.Nikoudel, N.Hafezi Moghaddas…, 2014: Engineering geological conditions of the Holocene sediments of Anzali area, South Caspian Coast, North Iran. A broad assessment of the geological, sedimentological, and geotechnical characteristics of the coastal Holocene sediments of Anzali Area (North Iran) was made to provide a useful guide for development, planning, and construction. Based on the sed...

Lahmeyer, H.W.; Reynolds, C.F.; Kupfer, D.J.; King, R., 1989: Biologic markers in borderline personality disorder: a review. The use of biologic markers in the evaluation of borderline personality disorder (BPD) patients is reviewed. Many patients with Axis II BPD have coexisting Axis I diagnoses of which depression is the most commonly reported. Biologic markers have n...