+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A proteomic approach for exploring biofilm in Streptococcus mutans

, : A proteomic approach for exploring biofilm in Streptococcus mutans. Bioinformation 5(10): 440-445

Biofilm formation by Streptococcus mutans is considered as its principal virulence factor, causing dental caries. Mutants of S. mutans defective in biofilm formation were generated and analyzed to study the collective role of proteins in its formation. Mutants were characterized on the basis of adherence to saliva-coated surface, and biofilm formation. The confocal laser microscopy and scanning electron microscopy images showed that the control biofilms had cluster of cells covered by layer of exo-polysaccharide while the biofilms of mutants were thin and spaced. Two-dimensional protein electrophoresis data analysis identified 57 proteins that are either up (44 proteins) or down (13 proteins) regulated. These data points to the importance of up and down regulated proteins in the formation of biofilm in Streptococcus mutans.


PMID: 21423890

Other references

Petersen Joerg; Papenberg Cord; Klaeschen Dirk, 2002: Gas hydrate reservoir characterization at Hydrate Ridge using PS converted waves from ocean bottom seismometer (OBS) data. Eos, Transactions, American Geophysical Union: 7, Suppl., Pages 762. 2002.

Restall B.J., 1992: Seasonal variation in reproductive activity in australian goats. Seasonal variation in reproductive activity in Australian goats was investigated in three experiments. In the first, the seasonal incidence of spontaneous ovulations was recorded by monthly endoscopy in mature does and young sheep separated from m...

Michetti, Jérôme.; Maret, D.; Mallet, J-Philippe.; Diemer, F., 2010: Validation of cone beam computed tomography as a tool to explore root canal anatomy. Cone beam computed tomography (CBCT) can provide dentists with high-quality 3-dimensional images of dental structures because of its high spatial resolution. The reconstructions of root canal systems given by the Kodak 9000 3D were compared with h...

Hudson, J.W.; Rummel, J.A., 1966: Water metabolism and temperature regulation on the primitive heteromyids, Lyomys salvani and Lyomys irroratus. Ecology, 47: 345-354

Bourne, JM., 1987: Black honeyeater breeding in the south east of South Australia. South Australian Ornithologist, 303: 77

Greaney, F.J.; Machacek, J.E., 1942: Prevalence of seed-borne fungi on cereals in certain seed inspection districts of Canada. Seed surveys and pathological tests were made to determine the relative prevalence of disease-producing organisms in the seed of wheat, oats, barley and rye produced in different districts of Canada in 1939 and 1940, and to ascertain the effect of...

Copp, G.H., 2014: The Fish Invasiveness Screening Kit (FISK) for non-native freshwater fishes--a summary of current applications. Risk Analysis 33(8): 1394-1396

Garnier, R.; Riboulet-Delmas, G.; Chatenet, T.; Efthymiou, M.L., 1986: Acute pentoxifylline poisoning in children. Annales de Pediatrie 33(1): 62-63

Quinn, T.W.; White, B.N., 1987: Identification of restriction-fragment-length polymorphisms in genomic DNA of the lesser snow goose (Anser caerulescens caerulescens). A genomic library of partially EcoRI-digested DNA from the lesser snow goose, Anser caerulescens caerulescens, was constructed in the phage vector Charon 4. Phage containing only unique sequences were identified by screening plaques with 32P-label...

Voong, K.Ranh.; Davison, J.; Pawlik, T.M.; Uy, M.O.; Hsu, C.C.; Winter, J.; Hruban, R.H.; Laheru, D.; Rudra, S.; Swartz, M.J.; Nathan, H.; Edil, B.H.; Schulick, R.; Cameron, J.L.; Wolfgang, C.L.; Herman, J.M., 2009: Resected pancreatic adenosquamous carcinoma: clinicopathologic review and evaluation of adjuvant chemotherapy and radiation in 38 patients. Pancreatic adenosquamous carcinoma is a rare morphological variant of pancreatic adenocarcinoma with an especially poor prognosis. The purpose of this study is to identify clinicopathologic features associated with prognosis, assess whether the pe...