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Acute lymphoblastic leukemia presenting as a breast lump: A report of two cases

, : Acute lymphoblastic leukemia presenting as a breast lump: A report of two cases. Journal of Cytology 30(3): 201-203

Extra-medullary leukemic infiltration of the breast by acute lymphoblastic leukemia (ALL) is very rare. We report two cases of ALL presenting as breast masses and diagnosed on fine-needle aspiration (FNA). Our first patient, a post-partum 30-year-old female, developed bilateral breast lumps in her last trimester of pregnancy and complained of easy fatigability. Our second patient, a 14-year-old girl, presented with a right-breast lump of 1-week duration. She had received treatment for ALL 1 year back and had been in complete remission for the last 1 year. FNA of the breast nodules done in both the cases revealed diffuse infiltration by lymphoblasts. Subsequent hematological investigations confirmed bone marrow involvement by ALL in the first case and extra-medullary relapse in the second case. Fine-needle aspiration cytology (FNAC) is an easy and cost effective method for the early diagnosis of metastatic leukemic infiltration, avoiding unnecessary excisional biopsies in such cases.


PMID: 24130415

DOI: 10.4103/0970-9371.117644

Other references

Kulakov, V.I.; Vikhliaeva, E.M., 1995: Infectious diseases of the female reproductive system. Akusherstvo i Ginekologiia: 3-6

Waller, B.F., 1988: The old-age heart: normal aging changes which can produce or mimic cardiac disease. The elderly segment of our society may triple by the year 2050. Specific cardiovascular data on the normal aging heart will be needed to provide proper medical and surgical therapy for this patient group. This report reviews normal aging changes o...

Placidi, L.; Roussel, A., 1964: On Microbial Contamination Of Food Products (Milk, Meats). Revue D'hygiene et de Medecine Sociale 12: 391-402

Chah, E.; Hok, V.; O'Mara, S.M.; Reilly, R.B., 2012: A waveform independent cell identification method to study long-term variability of spike recordings. Extracellular potential recordings are important in neuroscience; however the variability of spike waveforms has not been extensively studied to date. This study examines the variability of spike recordings within and between sessions. Place cell...

Ziegler, F.; Maley, F.T.imble, R., 1988: Characterization of the glycosylation sites in yeast external invertase. II. Location of the endo-beta-acetylglucosaminidase H-resistance sequons. Journal of biological chemistry, 263(15): 6986-6992

Nagel, G.; Bjørge, T.; Stocks, T.; Manjer, J.; Hallmans, G.; Edlinger, M.; Häggström, C.; Engeland, A.; Johansen, D.; Kleiner, A.; Selmer, R.; Ulmer, H.; Tretli, S.; Jonsson, H.; Concin, H.; Stattin, P.; Lukanova, A., 2012: Metabolic risk factors and skin cancer in the Metabolic Syndrome and Cancer Project (Me-Can). Little is known about the associations of metabolic aberrations with malignant melanoma (MM) and nonmelanoma skin cancer (NMSC). To assess the associations between metabolic factors (both individually and combined) and the risk of skin cancer in t...

Mader, T.L.; Dahlquist, J.M.; Britton, R.A.; Krause, V.E., 1991: Type and mixtures of high-moisture corn in beef cattle finishing diets. In three experiments consisting of three finishing trials each, five corn storage and(or) feeding treatments were evaluated: 1) dry whole (DWC); 2) whole high-moisture (WHMC); 3) mixture (MHMC) of ground (GHMC) or rolled (RHMC) high-moisture corn...

Malik, N.; Kotecha, A.; Gold, S.; Asfor, A.; Ren, J.; Huiskonen, J.T.; Tuthill, T.J.; Fry, E.E.; Stuart, D.I., 2017: Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation. Foot-and-mouth disease virus (FMDV) belongs to the Aphthovirus genus of the Picornaviridae, a family of small, icosahedral, non-enveloped, single-stranded RNA viruses. It is a highly infectious pathogen and is one of the biggest hindrances to the...

Sanna, A., 1951: Investigations on the presumed intestinal synthesis of vitamin B2. Anales de Medicina Publica 3(1-4): 201-204

Schlagenhauf, P.; Steffen, R.; Loutan, L., 2003: Migrants as a major risk group for imported malaria in European countries. Searches of MEDLINE and national malaria statistics were conducted, and reports and studies showing the proportion of malaria cases occurring in non-nationals in European countries were analysed. The period of the search was January 1991-September...