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Adherence to antibiotherapy guidelines for acute community-acquired pneumonia in adults, in a teaching hospital

, : Adherence to antibiotherapy guidelines for acute community-acquired pneumonia in adults, in a teaching hospital. Medecine et Maladies Infectieuses 40(8): 468-475

The authors had for aim to assess the conformity of antibiotic prescription with guidelines, for the management of community-acquired pneumonia, in a French University Hospital. This prospective study included adults patients hospitalized for pneumonia over a period of six months. The attending physician estimated the severity of pneumonia. The adequacy to guidelines focused on: first antibiotic choice and prescription modality, antibiotic choice in case of treatment modification at 48 to 72 hours, and duration of antibiotherapy. A hundred and nine cases of pneumonia were included in 106 patients. The mean age was 66 years, the mortality rate was 17 %. Bacterial documentation was recorded in 40.4 % of cases. The first antibiotics used were in accordance with guidelines in 52.3 % of cases. The non conformity rate was minor in 55.8 % of cases. Antibiotherapies putting the patient at risk were used in less than 10 % of the cases. The rate of antibiotic modification at 48 to 72 hours was 46.8 %, primarily for bacteriological purposes (35.3 %) or initial treatment failure (27.4 %). The treatment duration was inappropriate in 52.7 % of cases and generally too long in case of non conformity. It seems important to support guideline information, training of prescribers, and to consult an antibiotic expert.


PMID: 20171030

DOI: 10.1016/j.medmal.2010.01.009

Other references

Stuart, A.M.; Bloomquist, J.R.; Soderlund, D.M., 1987: Pharmacological characterization of the voltage-dependent sodium channels of rainbow trout brain synaptosomes. Batrachotoxin, aconitine, and veratridine, alkaloid activators of voltage-dependent sodium channels, stimulated 22Na+ uptake by rainbow trout brain synaptosomes. The potency and efficacy of activation by these compounds decreased in the following...

Court J.H., 1968: Manic depressive psychosis an alternative conceptual model human. British Journal of Psychiatry 114(517): 1523-1530

Harter L.P.; Gross B.H.; S.H.laire J.; Filly R.A.; Goldberg H.I., 1982: Computed tomographic and sonographic appearance of hepatic vein obstruction. AJR (American Journal of Roentgenology) 139(1): 176-178

Troller, Ja, 1977: Statistical analysis of aw measurements obtained with the Sina scope. Journal of food science: 42 (1) 86-90

Lesueur,C.; Knittl,P.; Gartner,M., 2010: Pesticide contamination of the organic farming cereals on the Austrian market from 2003 to 2007. From 2003 to 2007, 7,500 organic farming cereals from Austria were analysed with GC-MS after extraction according to the DFG S19 method. Organic farming is characterized by the prohibition of pesticide use that is achieved in praxis with maximum a...

Ali, S.Z.; Kurz, A., 2004: Methylnaltrexone and alvimopan: economic management of opioid-induced bowel dysfunction. The occurrence of opioid-induced bowel dysfunction is common in the postoperative period and in chronic pain conditions. This debilitating adverse effect involves the activation of peripheral opioid receptors causing delayed recovery of normal col...

Reddering J.S.V.; Rust I.C., 1990: Projected long term effects of river damming on small, microtidal estuaries, south-eastern Cape Province, South Africa. International Sedimentological Congress 13: 453-454

Miller, L.S.; Daigle, D.P., 2001: Apparatus and method for catheterization of blood vessels. A catheter insertion device is disclosed herein. The device allows an operator to insert a catheter within a vessel with a single hand enabling the operator to keep a grip on the patient's skin and vessel. The device also includes a needle ti...

Haseltine, SD.; Fair, JS.; Sutcliffe, SA.; Swineford, DM., 1983: Trends in organochlorine and mercury residues in common loon (Gavia immer) eggs from New Hampshire. Transactions of the Northeast Fish and Wildlife Conference, 40: 131-141

Bito, S.; Fukuhara, S.; Kurokawa, K., 1999: What factors are related to autonomy preferences and their serial changes?. JGIM 14(SUPPL 2): 11, April