+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Aerobic physical training restores biomechanical properties of Achilles tendon in rats chemically induced to diabetes mellitus

, : Aerobic physical training restores biomechanical properties of Achilles tendon in rats chemically induced to diabetes mellitus. Journal of Diabetes and Its Complications 26(3): 163-168

The aim of this study is to evaluate if the application of a moderate aerobic exercise protocol reverses the damage caused by diabetes on the mechanical properties of the Achilles tendon. Forty-four rats were divided randomly into four groups as follows: Sedentary Control Group-SCG, Sedentary Diabetic Group-SDG, Trained Control Group-TCG and Trained Diabetic Group-TDG, the trained groups were submitted to a protocol of moderate physical training on a continuous treadmill. For mechanical testing the tendons were fixed in a conventional mechanical testing machine and pulled to the point of failure of the specimen, the cell load of 500N. The parameters were: Elastic Modulus (MPa), Stress Maximum Strength (MPa), Strain Specific Maximum Force (mm), Energy / Tendon Area ( and Cross-sectional Area (mm(2)). The evaluation of the biomechanical properties of the Achilles tendon of the SDG indicated that the elastic modulus (MPa) is decreased when compared to the TDG and the other groups (p<0.01). However, the specific deformation (%), the deformation at maximum force (mm), and energy / tendon area ( of the SDG were significantly higher than in the other groups (p<0.01). Moreover, moderate aerobic training on a treadmill caused the biomechanical property values to move closer to the values shown by the control groups (p>0.01). In summary, our study indicates that moderate-intensity aerobic training restored the normal mechanical properties of tendons in diabetic animals, since the elastic modulus (MPa), the specific deformation (%), the deformation of the maximum force (mm) and energy / tendon area ( approached the values shown by the control groups.


PMID: 22520401

DOI: 10.1016/j.jdiacomp.2012.03.017

Other references

Kojima, K.; Omoto, E.; Katayama, Y.; Uno, M.; Takada, I.; Kimura, G.; Kanehiro, A.; Tada, S.; Hayashi, K.; Kimura, I.; Sanada, H.; Harada, M., 1996: Autoimmune hemolytic anemia in allergic granulomatous angitis (Churg-Strauss syndrome). We describe a patient with allergic granulomatous angitis who developed autoimmune hemolytic anemia (AIHA). A 44-year-old male had been suffering from bronchial asthma. On admission, laboratory tests revealed the presence of severe eosinophilia (2...

Kyriazakis I.; Emmans G.C.; Whittemore C.T., 1989: The effect of body composition on diet selection of growing pigs. Animal Production 48(3): 627

Moore, W.P.; Gale, E.A.M.; Group, E., 1997: Feasibility of a multinational diabetes prevention trial in first degree relatives of a child with IDDM. Diabetologia 40(SUPPL 1): A67

Hockey, K.C., 1966: Chilling requirements of apple trees. One-year-old Delicious trees on M.IX rootstocks were grown in pots for one growing season. In April some were transferred to a glasshouse where the temperatures in the winter never fell below 50 degrees F. Some were left outside all winter and oth...

Mochinaga, S.; Okahashi, T.; Koga, S.; Nakano, Y.; Yakabe, T.; Sumi, K.; Kitahara, K.; Noshiro, H.; Kimura, S.; Fujito, H., 2012: Effects of reduced dose intensity of modified FOLFOX6 in patients with metastatic or recurrent colorectal cancer. The current study was conducted to retrospectively investigate the effects of reducing average relative dose intensity (ARDI) in response to adverse events on time to treatment failure (TTF) and overall survival (OS) in patients with metastatic or...

Balduini, W.; Cimino, M.; Reno, F.; Marini, P.; Princivalle, A.; Cattabeni, F., 1993: Effects of postnatal or adult chronic acetylcholinesterase inhibition on muscarinic receptors, phosphoinositide turnover and m-1 mRNA expression. Muscarinic receptor number, receptor-stimulated phosphoinositide hydrolysis and m-1 mRNA expression were examined in the cerebral cortex and hippocampus of rats treated during postnatal development or in adult age with the organophosphate diisopro...

Rizzetto, M., 2009: Liver transplantation and management of the hepatitis B virus. Preface. Digestive and Liver Disease 41 Suppl 2: S183-S183

Caughlin, T.; Wheeler, J.H.; Jankowski, J.; Lichstein, J.W., 2012: Urbanized landscapes favored by fig-eating birds increase invasive but not native juvenile strangler fig abundance. Propagule pressure can determine the success or failure of invasive plant range expansion. Range expansion takes place at large spatial scales, often encompassing many types of land cover, yet the effect of landscape context on propagule pressure...

Macdonald, R.Loch., 2015: When in Rome, do as the Romans do?. World Neurosurgery 84(3): 638-639

Bagheri-Nesami, M.; Gorji, M.Ali.Heidari.; Rezaie, S.; Pouresmail, Z.; Cherati, J.Yazdani., 2015: Effect of acupressure with valerian oil 2.5% on the quality and quantity of sleep in patients with acute coronary syndrome in a cardiac intensive care unit. The purpose of this three-group double-blind clinical trial study was to investigate the effect of acupressure ( zhǐ yā) with valerian ( xié cǎo) oil 2.5% on the quality and quantity of sleep in patients with acute coronary syndrome (ACS) in a...