geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Aflatoxin B₁ and M₁ in milk


, : Aflatoxin B₁ and M₁ in milk. Analytica Chimica Acta 829: 68-74

The aflatoxin M1 (AFLAM1) is a mycotoxin that results from the hydroxylation of the aflatoxin B1 (AFLAB1). It contaminates the milk of animals fed with a diet containing its precursor. In this work, we determined the occurrence of AFLAB1 and AFLAM1 in milk, as well as the chromatographic conditions to quantify these mycotoxins. The extraction and quantification of AFLAB1 and AFLAM1 in naturally contaminated and artificially spiked milk samples which are produced and marketed in the state of RS were performed using the AOAC official method and UHPLC with fluorescence detection. We obtained a separation factor of 2.3 for AFLAB1 and AFLAM1 using a mobile phase consisting of 1% acetic acid:acetonitrile:methanol (55:10:35). The analytical curves had a wide linearity range and the limit of quantification (LOQm) concentrations of AFLAB1 and AFLAM1 were equal to 0.5 and 0.25 μg L(-1), respectively. Samples of pasteurized and ultra-high-temperature processed (UHT) milk showed natural contamination, and the levels for both aflatoxins ranged from 0.7 to 1.5 μg L(-1). Raw and concentrated milk samples only contained AFLAM1, with a maximum average concentration of 1.7 μg L(-1). These concentrations, higher than permitted by legislation, confirm the existence of a health risk, as well as highlight the relevance of searching for alternatives to reduce this contamination.

US$19.90

PMID: 24856405

DOI: 10.1016/j.aca.2014.04.036


Other references

Goodstadt M., 1974: International symposia on alcohol and drug addiction research on methods and programs of drug education. International Symposia on Alcohol And Drug Addiction Research on Methods And Programs Of Drug Education 191

Kenyon, D.; Yang, T.T.; Ambrosio, T., 2000: Retention of dose uniformity with the new mometasone furoate dry powder inhaler. Journal of Allergy & Clinical Immunology 105(1 part 2): S14-S15, Jan

D.Lima G.R., 1971: Estriol as a feto placentary unit function test. Go Revista de Atualizacao em Ginecologia e Obstetricia 5(12): 6-9

Park, L.G.; Collins, E.G.; Shim, J.K.; Whooley, M.A., 2017: Comparing Mobile Health Strategies to Improve Medication Adherence for Veterans With Coronary Heart Disease (Mobile4Meds): Protocol for a Mixed-Methods Study. Adherence to antiplatelet medications is critical to prevent life threatening complications (ie, stent thrombosis) after percutaneous coronary interventions (PCIs), yet rates of nonadherence range from 21-57% by 12 months. Mobile interventions del...

Watanabe, J.; Tasaki, K., 1980: Shift-effect in the rabbit retinal ganglion cells. Brain Research 181(1): 198-201

Liu, Tj, 1975: The genus Abies. X. Quarterly journal: 28 (3 4) 483-547

Budvytyte, A., 2002: Plant Genetic Resources (PGR) seed collections and their conservation prospects in the Lithuanian Genebank. The main objective of this work was to determine how seed of different plant species tolerate long-term storage conditions in the newly established National Genebank. The study was conducted with 33 species representing 876 accessions. Germination...

Coplan, N.L.; Shimony, R.Y.; Ioachim, H.L.; Wilentz, J.R.; Posner, D.H.; Lipschitz, A.; Ruden, R.A.; Bruno, M.S.; Sherrid, M.V.; Gaetz, H., 1990: Primary pulmonary hypertension associated with human immunodeficiency viral infection. American Journal of Medicine 89(1): 96-99

Thipphawong, J.; Otulana, B.; Clauson, P.; Okikawa, J.; Farr, S.J., 2002: Pulmonary insulin administration using the AERx insulin diabetes system. Diabetes Technology & Therapeutics 4(4): 499-504

Sullivan, A.C.; Singh, M.; Srere, P.A.; Glusker, J.P., 1977: Reactivity and inhibitor potential of hydroxycitrate isomers with citrate synthase, citrate lyase, and ATP citrate lyase. The four isomers of hydroxycitrate have been tested as substrates and inhibitors for citrate synthase, citrate lyase, and ATP citrate lyase. None of the isomers served as a substrate for citrate synthase and they were moderate to weak inhibitors o...