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Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress

, : Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress. Pharmacology, Biochemistry, and Behavior 111(): 128-135

Theanine, an amino acid in tea, has significant anti-stress effect on experimental animals under psychosocial stress. Anti-stress effect of theanine on humans was evaluated in 5th-year university students during pharmacy practice. The study design was a single-blind group comparison and participants (n=20) were randomly assigned to theanine or placebo groups. Theanine or placebo (lactose) tablets (200 mg, twice a day, after breakfast and lunch) were taken from 1 week prior to the pharmacy practice and continued for 10 days in the practice period. To assess the anxiety of the participants, the state-trait anxiety inventory test was carried out before the pharmacy practice. Salivary α-amylase activity (sAA) was measured as a marker of sympathetic nervous system activity. In the placebo-group, sAA in the morning (pre-practice sAA) was higher than in theanine-group during the pharmacy practice (p=0.032). Subjective stress was significantly lower in the theanine-group than in the placebo-group (p=0.020). These results suggest that theanine intake had anti-stress effect on students. Furthermore, students with higher pre-practice sAA showed significantly higher trait anxiety in both groups (p=0.015). Similarly, higher pre-practice sAA was correlated to shorter sleeping time in both groups (p=0.41×10(-3)). Stressful condition increased the level of sAA that was essentially affected by individual trait anxiety. The low levels of pre-practice sAA and subjective stress in the theanine-group suggest that theanine intake suppressed initial stress response of students assigned for a long-term commitment of pharmacy practice.


PMID: 24051231

DOI: 10.1016/j.pbb.2013.09.004

Other references

Hatcher, P.D.; Brown, V.J.; Tait, D.S.; Bate, S.; Overend, P.; Hagan, J.J.; Jones, D.N.C., 2005: 5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats. Rationale and objective: Performance on the Wisconsin Card Sorting Test (WCST), which requires patients to 'shift attention' between stimulus dimensions (sorting categories), is impaired in diseases such as schizophrenia. The rat attenti...

Hubbell, J.A.; Kieras, M.T.; Ron, E.S.; Rowe, S.C., 2000: Biodegradable macromers for the controlled release of biologically active substances. A method for delivering a biologically active substance including the steps of: (a) combining said biologically active substance with a macromer; (b) forming a mixture of the combination formed in step (a); (c) polymerizing said mixture to form ar...

Reitz, J., 1970: New means of controlling weeds in forestry. Forst und Holzwirt: 25 (5) 88-90

Longland, C.J.; Ives, J.C., 1965: Endemic Staphylococcal Sepsis In A Surgical Unit. Records of staphylococcal sepsis encountered in hospital are few though the literature of wound infection alone is large. All forms of staphylococcal sepsis current in 3 general surgical wards have been recorded, using weekly counts of patients ex...

Mabrouk, N.; Berriche, H., 2014: Theoretical study of the CsNa molecule: adiabatic and diabatic potential energy and dipole moment. The adiabatic and diabatic potential energy curves of the low-lying electronic states of the NaCs molecule dissociating into Na (3s, 3p) + Cs (6s, 6p, 5d, 7s, 7p, 6d, 8s, 4f) have been investigated. The molecular calculations are performed using a...

Karaoulanis, Gd, 1979: Biochemical changes in Washington navel oranges during their growing and under different storage conditions. Progress in refrigeration science and technology proceedings of the XIV International Congress of Refrigeration = Progres dans la science et la technique du froid: comptes rendus du XIV Congres international du froid edited by the Organizing Committee and the Papers Committee XIV International Congress of Refrigeration USSR National Committee for IIR: 845

Ronai, T., 1960: Operated disk hernia migrated to the posterior wall of the dural sac causing acute caudal syndrome. Orvosi Hetilap 101: 842-843

Otani, T.; Ueki, K.; Cho, K.; Kanai, K.; Tateno, K.; Saito, T., 2016: Construction of dibenzo-fused seven- to nine-membered carbocycles via Brønsted acid-promoted intramolecular Friedel-Crafts-type alkenylation. Brønsted acid-promoted intramolecular hydroarylation of alkynylbenzenes carrying an arylalkyl group at the ortho-position leads to alkylidenedibenzo[a,d]cycloheptenes, -octenes and -nonenes in up to quantitative yield with complete regioselectivi...

Voltz, R.; Hohlfeld, R., 1992: Current treatment of multiple sclerosis High-dosage intravenous therapy with corticosteroids. Nervenarzt 63(12): 773-775

Jeremiah, Z.A.; Buseri, F.I.; Uko, E.K., 2007: Iron deficiency anaemia and evaluation of the utility of iron deficiency indicators among healthy Nigerian children. The hemoglobin (Hb), serum iron (SI), total iron binding capacity (TIBC), transferrin saturation (TS) and serum ferritin (SF) values of 240 apparently healthy children were determined in a prospective cross-sectional study conducted in Port Harcou...