geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Antibiotic-coated spacers for total hip arthroplasty infection


, : Antibiotic-coated spacers for total hip arthroplasty infection. Orthopedics 33(9): 649-649

Total hip arthroplasty (THA) infection imposes a significant burden on the patient and the health care system. Two-stage revision with interval placement of an antibiotic-cement spacer is the standard of care for chronic periprosthetic infections. This treatment allows for the direct delivery of antibiotics to the infected tissues, and maintains soft tissue tension to facilitate the re-implantation procedure. Evidence suggests that articulating spacers, compared to nonarticulating designs, enhance postoperative ambulation and make the second-stage procedure less difficult. Prefabricated spacers are easy to use; however, they cannot be used to alter the antibiotic composition and dosage. Custom-molded spacers prepared in the operating room from commercially available kits are a popular option; however, like prefabricated spacers, limited sizes are available and thus, they may be contraindicated in situations with significant bone loss. Custom-made total hip spacers are significantly less expensive than commercially-available options, are useful in cases of bone loss, and optimize patient function prior to re-implantation. An inexpensive cemented femoral stem is covered with antibiotic-loaded bone cement. This is done once the cement has the consistency of dough to prevent interdigitation with the host femur. The authors use at least 3.6 g of tobramycin and 1 g of vancomycin per packet of cement. A thin polyethylene is cemented into the acetabulum, followed by placement of the femoral prosthesis. Combined component position must be optimized to prevent instability.

US$19.90

PMID: 20839700

DOI: 10.3928/01477447-20100722-21


Other references

Charoenlarp, K.; Jariya, P.; Junyandeegul, P.; Panyathanya, R.; Jaroonvesama, N., 1988: Primary amoebic meningoencephalitis: a second reported case in Thailand. A 17-year-old man presented in Bangkok, Thailand, in May 1986, with confusion, headache, fever, vomiting and blurred vision. The patient was semiconscious and had neck rigidity and positive Kernig's sign. The CSF was turbid, with a total cell...

Dugdale, J.S., 1994: Hepialidae (Insecta: Lepidoptera). The Hepialidae found in New Zealand are revised. Seven genera are recognised, including one new genus. Twenty-seven species are recognized, with 10 being described as new. The morphology of adults, pupae, larvae and the male genital musculature is...

Cowie R.A.; Hitchcock E.R., 1982: Late results of antero lateral cordotomy for pain relief. Antero-lateral cordotomy was carried out on 56 patients with intractable pain between 1968-1978. The follow-up of these patients was continued for at least 3 yr or until death to determine the late success of this procedure. Of 33 patients who und...

Bouckaert, J.J.; Pannier, R., 1941: Au sujet des influences reflexes de la pression veineuse sur les centres cardio-regulateurs, vasomoteur et respiratoire. Venous hypertension was induced in a dog B by anastomosing the cardiac end of one of his external jugular veins with the cardiac end of one common carotid of a dog A. By opening the anastomosis, a hypertension was produced in the venae cavae and i...

Krupka, J.; Dziedzic, R.; Drozd, L., 1990: Quality characteristics of deer bucks hunted in the macro-region of central-eastern Poland. Ann Univ Mariae Curie-Sklodowska Sect EE Zootech. 1986 ; 4: 7-14

Vaman, V.S.A.jana; Tinu, S.K.; Geetha, C.S.; Mohanan, P.V., 2012: Assessment of micronuclei and chromosomal anomalies of five biocompatible materials in mice. In vivo genetic toxicology tests measure direct DNA damage or the formation of gene or chromosomal mutations, and are used to predict mutagenic and carcinogenic potential of compounds for regulatory purposes. These adverse genotoxic effects may be...

Britto, R.Moreira.; Santos, Aé.Luiz.; Cruz, J.Santos.; Gondim, A.Nei.Santana.; Lauton-Santos, S.; Lara, A.; Guatimosim, S.; Vasconcelos, C.Maria.Lins.; Estevam, C.Dos.Santos.; Dias, A.Santos.; Oliveira, E.Diniz.; Lima, A.Karla.; Souza, R.Cardoso.; Conde-Garcia, E.Antonio., 2013: Aqueous fraction from Costus spiralis (Jacq.) Roscoe leaf reduces contractility by impairing the calcium inward current in the mammalian myocardium. Brazilian folk medicine uses infusion of Costus spiralis leaf to help people to treat arterial hypertension and syndromes of cardiac hyperexcitability. Evaluate the aqueous fraction (AqF) effect on atrial contractility and investigate its mechanis...

Sinulingga, W.; Tjitrosomo, H.S.S.; Pawirosoemardjo, S.; Rumawas, F., 1989: Effect of several cover crops on the intensity and viability of Rigidoporus lignosus on rubber trees. In studies in Indonesia, cover crops could not prevent infection once the pathogen had attacked the collar of the rubber tree, although they tended to reduce disease intensity through stimulating the growth of microorganisms, particularly bacteria...

Lieberman, E., 1978: Hypertension in childhood and adolescence. Clinical Symposia 30(3): 3-43

Wolff, S., 2003: Intragastric penetration of a gastric band -- a severe complication after gastric banding?. In morbid obese patients the adjustable laparoscopic gastric banding is an effective procedure with a widespread acceptance. Pouch dilatation, band slipping, port-penetration and port infection are the most known complications. We report on three...