geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Antigliadin antibodies in psoriasis


, : Antigliadin antibodies in psoriasis. Australasian Journal of Dermatology 51(4): 238-242

Although antigliadin antibodies (AGA) are markers of coeliac disease, elevated levels of these antibodies are also seen in many other autoimmune, neurological, haematological, collagen vascular and cutaneous disorders, even in the absence of clinically overt gastrointestinal disease. Several studies have reported an association between psoriasis and AGA, with improvement in severity of psoriasis on a gluten-free diet. This study aims to determine whether patients with psoriasis in Kashmir have an increased prevalence of elevated AGA. A total of 120 patients (all native Kashmiris) with psoriasis and an equal number of age- and sex-matched controls without any personal or family history of autoimmune disorders were included in the study. Both groups were tested for IgA and IgG AGAs using a standard enzyme-linked immunosorbent assay method. No statistically significant difference in the prevalence of AGA among patients with psoriasis (6.67% for IgA and 4.17% for IgG) and control group individuals (7.5% IgA and 5.0% IgG) was observed. The mean AGA levels in the two groups were not statistically different. Furthermore, no significant association between AGA levels and psoriasis severity, joint involvement, age of onset of psoriasis or arthritis was observed. The results of our study show that AGA are not elevated in psoriasis patients as compared with a healthy population, and there is no association between AGA and psoriasis, its onset, severity and joint symptoms.

US$19.90

PMID: 21198518

DOI: 10.1111/j.1440-0960.2010.00648.x


Other references

Runkle, J.R., 2013: Thirty-two years of change in an old-growth Ohio beech-maple forest. Old-growth forests dominated by understory-tolerant tree species are among forest types most likely to be in equilibrium. However, documentation of the degree to which they are in equilibrium over decades-long time periods is lacking. Changes in c...

Hao, Y.Jiang.; Chen, D.Quan.; Zhao, Q.Zhong.; Wang, D., 2007: Serum concentrations of gonadotropins and steroid hormones of Neophocaena phocaenoides asiaeorientalis in middle and lower regions of the Yangtze River. As a relatively isolated and unique freshwater population, the Yangtze finless porpoise (Neophocaena phocaenoides asiaeorientalis) is the most endangered subpopulation of this species. The objective of this study was to improve our understanding o...

Murao, S.; Shin, T.; Katsu, Y., 1987: Thiol proteinase inhibitor caricastatin, produced by a strain of Nigrosabulum novosp. Agricultural and Biological Chemistry 51: 29-31

Cicolani, B., 1980: Sulla biologia, ecologia e morfologia di Macrocheles vernalis (Berl.) (Acarina: Mesostigmata). Redia, 63: 441-457

Pankratz, L.; Jackson, J., 1994: Habitually wandering patients. Physicians are sometimes confronted with patients who gain admission to one hospital after another, sometimes referred to as "wandering patients." Little is known about the presenting symptoms of these patients, their use of hospital res...

Gould, E., 1965: An evaluation of Red Delicious sports. More than 50 bud-sport strains of the above apple are under evaluation. The promising standard-type selections include Topred, Dietrich, Houser, Chelan Red, Red Prince and Ryan Red, which have early and intensely coloured fruit. Of the semidwarf s...

Li, Q.; Zhang, W.; Miljanić, O.S.; Sue, C-Hau.; Zhao, Y-Li.; Liu, L.; Knobler, C.B.; Stoddart, J.Fraser.; Yaghi, O.M., 2009: Docking in metal-organic frameworks. The use of metal-organic frameworks (MOFs) so far has largely relied on nonspecific binding interactions to host small molecular guests. We used long organic struts (approximately 2 nanometers) incorporating 34- and 36-membered macrocyclic polyeth...

Xia, K.; Zhang, S.; Solina, B.A.; Barquera, B.; Colón, W., 2010: Do prokaryotes have more kinetically stable proteins than eukaryotic organisms?. Upon folding, some proteins become conformationally trapped, presumably to protect against aggregation or premature degradation. To probe the occurrence of this property, known as kinetic stability, we used a diagonal two-dimensional sodium dodecy...

Grifantini, R.; Bartolini, E.; Muzzi, A.; Draghi, M.; Frigimelica, E.; Berger, J.; Randazzo, F.; Grandi, G., 2003: Gene expression profile in Neisseria meningitidis and Neisseria lactamica upon host-cell contact: from basic research to vaccine development. Differential gene regulation in the human pathogen Neisseria meningitidis group B (MenB) and in Neisseria lactamica, a human commensal species, was studied by whole genome microarray after bacterial interaction with epithelial cells. Host-cell con...

Ojha, M.; Wallace, C.J., 1988: Novel Ca2+-activated neutral protease from an aquatic fungus, Allomyces arbuscula. A Ca2+-activated neutral protease was purified to homogeneity from an aquatic Phycomycete fungus, Allomyces arbuscula. It requires millimolar concentrations of Ca2+ for activation (1.8 to 2 mM for 50% activation). Sr2+ can replace Ca2+ but at high...