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Apoptosis in the colonic crypt, colorectal adenomata, and manipulation by chemoprevention


, : Apoptosis in the colonic crypt, colorectal adenomata, and manipulation by chemoprevention. Cancer Epidemiology, Biomarkers & Prevention 18(6): 1680-1687

This review discusses the biology and the methods of assessment of apoptosis, of which, the monoclonal antibody M30 would seem to be the most useful; the role of apoptosis in the etiology of colorectal cancer; and its use as a marker to monitor the beneficial effects of chemopreventative interventions to reduce the development of colorectal cancer within the context of clinical trials.

US$19.90

PMID: 19505899

DOI: 10.1158/1055-9965.EPI-09-0006


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