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Associations between HLA molecules and ophthalmologic diseases


, : Associations between HLA molecules and ophthalmologic diseases. Medical Science Monitor 16(9): Ra191-6

The aim of this review was to analyze associations between HLA (human leukocyte antigens) alleles described thus far and an array of ophthalmologic disorders. Highly polymorphic HLA molecules play a crucial role in immunological response to various pathogens. Due to environmental pressures exerted mostly by infectious factors in the past, population frequencies of particular alleles differ greatly and modulate immunological response in various diseases. Associations between HLA alleles and over 500 pathologies, mainly autoimmune, infective and inflammatory diseases, have been previously described. In the course of certain HLA-related diseases described so far, eye manifestations are present. In this paper we review the structure, function and linkage between HLA antigens, ophthalmologic diseases and systemic disorders with eye involvement.

US$29.90

PMID: 20802427


Other references

Solaiappan, U.; Sheriff, N.M.hamed, 1994: Effect of tillage practices and nitrogen application in cotton grown after rice. Indian Journal of Agronomy 39(2): 302-304

Kim, C.Joo.; Ueda, M.; Imai, T.; Sugiyama, J.; Kimura, S., 2017: Tuning the Viscoelasticity of Peptide Vesicles by Adjusting Hydrophobic Helical Blocks Comprising Amphiphilic Polypeptides. Amphiphilic block polypeptides of poly(sarcosine)-b-(l-Val-Aib)<sub>6</sub> and poly(sarcosine)-b-(l-Leu-Aib)<sub>6</sub> and their stereoisomers were self-assembled in water. Three kinds of binary systems of poly(sarcosine...

Heintz, N.H.; Houchens, C.R., 2004: RIP60 nucleic acid and polypeptide sequences and uses therefor. The invention relates to nucleic acids and encoded polypeptides from the human zinc finger protein RIP60. The invention provides, inter alia, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected...

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Kien-Tsing, B., 1922: Zur mikrotechnischen Bearbeitung von Knochenfischeiern. Zeitschrift fuer Wissenschaftliche Mikroskopie Leipzig, 39: 165-168

Lesnik, E.A.; Maslova, R.N.; VarshavskiÄ­, I.M., 1981: Influence of ionic strength and temperature on the structure of poly(G) in solution 1H replaced by 3H exchange method. Molekuliarnaia Biologiia 15(1): 161-166

Johnson, D.; Rai, S.; Milne, S., 2002: Olanzapine oro-dispersible (Velotab TM ) - an alternative to depot?. Olanzapine oro-dispersible (Velotab TM ) was introduced to the United Kingdom in May 2000. It rapidly dissolves in the mouth, and therefore patients may find it preferable to swallowing tablets. Another advantage is that the opportunity to hide th...

Bharat Metkar; Pal, S.C.; Veena Kasture; Sanjay Kasture, 1999: Antidepressant activity of Nardostachys jatamansi DC. The antidepressant activity of roots and rhizomes of N. jatamansi was assessed using behavioural despair test, tail suspension test and ptosis antagonism in mice. The acetone soluble part of petroleum ether extract and its chloroform soluble fract...

Schaalje, G.B.; Butts, R.A.; Lysyk, T.J., 1991: Simulation studies of binomial sampling: a new variance estimator and density predictor, with special reference to the Russian wheat aphid (Homoptera: Aphididae). Standard methods of obtaining absolute population estimates for the Russian wheat aphid, Diuraphis noxia (Mordvilko), are not feasible because of the insect's small size, aggregated distribution, and difficulty in handling the samples. Becaus...

Salimi, Z.; Wolverson, M.K.; Herbold, D.R.; Vas, W.; Salimi, A., 1987: Treatment of frostbite with i.v. streptokinase: an experimental study in rabbits. Experiments were conducted in 32 rabbits to determine whether treatment with IV streptokinase can effectively limit the extent of tissue damage associated with frostbite injury of the hind limbs. Other variables studied were the temperature of the...