geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Biomimetic materials for medical application through enzymatic modification


, : Biomimetic materials for medical application through enzymatic modification. Advances in Biochemical Engineering/Biotechnology 125: 181-205

Living organisms synthesize functional materials, based on proteins and polysaccharides, using enzyme-catalyzed reactions. According to the biomimetic approach, biomaterial matrices for tissue engineering are designed to be able to mimic the properties and the functions of the extracellular matrix (ECM). In this chapter, the most significant research efforts dedicated to the study and the preparation of biomimetic materials through enzymatic modifications were reviewed. The functionalizations of different polymeric matrices obtained through the catalytic activity of two enzymes (Transglutaminase, TGase and Tyrosinase, TYRase) were discussed. Specifically, the biomimetic applications of TGase and TYRase to confer appropriate biomimetic properties to the biomaterials, such as the possibility to obtain in situ gelling hydrogels and the incorporation of bioactive molecules (growth factors) and cell-binding peptides into the scaffolds, were reviewed.

US$19.90

PMID: 21072699

DOI: 10.1007/10_2010_85


Other references

Tsukamoto, M.; Oki, Y.; Aoki, T., 2014: Using electronic medical records to identify outpatients receiving opioids who may benefit from intervention by our palliative care team. To achieve optimal management of cancer pain in our outpatients. All cancer patients in our outpatient department who received opioids. A pharmacist and a nurse of the palliative care team used electronic medical records(EMRs)to review cases of ou...

Hansen, A.L.; Dahl, L.; Olson, G.; Thornton, D.; Graff, I.E.; Frøyland, L.; Thayer, J.F.; Pallesen, S., 2015: Fish consumption, sleep, daily functioning, and heart rate variability. This study investigated the effects of fatty fish on sleep, daily functioning and biomarkers such as heart rate variability (HRV), vitamin D status (serum 25-hydroxyvitamin D (25OHD), and eicosapentaenoic acid (EPA, 20:5n-3) + docosahexaenoic acid...

Green, A., 1997: Notes on cancer management from a visiting Australian researcher. Japanese Journal of Clinical Oncology 27(2): 120-120

Giovanni Coco; A.B.ad Murray; Malcolm O.G.een, 2007: Sorted bed forms as self-organized patterns; 1, Model development. Journal of Geophysical Research: Earth Surface 112(F3)

Deeks, M.J.; Kaloriti, D.; Davies, B.; Malhó, R.; Hussey, P.J., 2004: Arabidopsis NAP1 is essential for Arp2/3-dependent trichome morphogenesis. The dynamic nature of the eukaryotic actin cytoskeleton is essential for the locomotion of animal cells and the morphogenesis of plant and fungal cells. The F-actin nucleating/branching activity of the Arp2/3 complex is a key function for all of t...

Vassilenko, SK.; Boutorin, AS.; Maev, SP.; Vityugov, FJ.; Boldyreva, LG.; Ryte, VK., 1983: Specificity of Middle Asian cobra (Naja naja oxiana) venom nuclease to polyribonucleotide macrostructure. Molekulyarnaya Biologiya (Moscow): 174: 818-826

Seibert, K.; Holland, M.; Weinstein, A., 1978: Medical grand rounds from the Dempsey Hospital of the University of Connecticut: Gout. Connecticut Medicine 42(6): 369-373

Savu, L.; Vranckx, R.; Maya, M.; Nunez, E.A., 1987: A thyroxine binding globulin (TBG)-like protein in the sera of developing and adult rats. We report evidence based on equilibrium binding, electrophoretic, autoradiographic studies, that the rat possesses a major high affinity thyroid hormone binding protein, with an electrophoretic mobility and binding properties similar to those of t...

Haider, K.; Shahid, R.K.; Finch, D.; Sami, A.; Ahmad, I.; Yadav, S.; Alvi, R.; Popkin, D.; Ahmed, S., 2006: Extrapulmonary small cell cancer: a Canadian province's experience. BACKGROUND. The objective of this study was to determine variables that correlate with the survival of patients with extrapulmonary small cell carcinoma (EPSCC).METHODS. Medical records of 101 eligible patients with EPSCC who were diagnosed in Sa...

Granfors, T.; Bergh, A.; Lofroth, P.-Olov; Widmark, A., 1999: Fractionated radiotherapy of rat prostatic adenocarcinoma (Dunning R3327-PAP) in nonanesthetized animals. BACKGROUND. The dose-response effect of fractionated external beam radiotherapy on nonanesthetized rats bearing the androgen-sensitive prostatic adenocarcinoma Dunning R3327-PAP was studied. METHODS. The radiation was given with a photon beam from...