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Biomimetic pseudopolyrotaxane prodrug micelles with high drug content for intracellular drug delivery

, : Biomimetic pseudopolyrotaxane prodrug micelles with high drug content for intracellular drug delivery. Chemical Communications 49(64): 7123-7125

For the first time, pseudopolyrotaxane prodrug micelles with high drug content were prepared in water, which could be used for cancer therapy. It is anticipated that this facile strategy may open a novel avenue for the development of multifunctional drug delivery systems.


PMID: 23828234

DOI: 10.1039/c3cc43687j

Other references

Cutherbert, J.A.; Lipsky, P.E., 1993: Selective suppression of activated p21ras-dependent proliferation by fluoromevalonate. Journal of Cellular Biochemistry Supplement 0(17 PART A): 279

Saletta, F.; Suryo Rahmanto, Y.; Siafakas, A.R.; Richardson, D.R., 2011: Cellular iron depletion and the mechanisms involved in the iron-dependent regulation of the growth arrest and DNA damage family of genes. Iron plays a crucial part in proliferation while iron deficiency results in G(1)/S arrest, DNA damage, and apoptosis. However, the precise role of iron in cell cycle control remains unclear. We showed that iron depletion using the iron chelators,...

Barna I.; Barna R., 1984: Hemoperitoneum produced by uterine perforation by placenta accreta destruens. Revista de Pediatrie Obstetrica si Ginecologie Seria Obstetrica si Ginecologie 32(4): 363-367

Milos, V.; Westerlund, T.; Midlöv, P.; Strandberg, E.Lena., 2015: Swedish general practitioners' attitudes towards treatment guidelines - a qualitative study. Drug therapy in primary care is a challenge for general practitioners (GPs) and the prescribing decision is influenced by several factors. GPs obtain drug information in different ways, from evidence-based sources, their own or others' experi...

Verhagen, J.; Geuyen, T.; Verstegen, M., 1983: Temperature requirements of pregnant sows in relation to the feeding level and the housing system. Bedrijfsontwikkeling 14(4): 299-303

Palsson, B.O., 1999: Targeted system for removing tumor cells from cell populations. Official Gazette of the United States Patent & Trademark Office Patents 1219(4): 3314, Feb 23

Balint, G.A.; Karácsony, G.; Varró, V., 1985: The effect of long-term prostacyclin treatment on the protein, DNA and RNA content of rat gastric fundic mucosa. The changes of gastric fundic mucosal protein, DNA and RNA content have been investigated during long-term (40 and 80 days respectively), prostacyclin treatment. It seems that a longer prostacyclin treatment induces a significant thickening of the...

Paine, M.L.; Gibbins, J.R.; Whitelock, J.M.; O'Grady, R.L.; Kefford, R.F., 1993: Unregulated and independent expression of collagenase and transin related to tumor progression. Journal of the National Cancer Institute 85(17): 1425-1427

Anonymous, 2011: Supercritical carbon dioxide SC-CO2 extraction ofNigella sativaL oil using full factorial design. In this study,Nigella sativaL. oil was extracted using supercritical carbon dioxide with full factorial design to determine the best extraction condition (pressure, temperature and dynamic extraction time) for obtaining an extract with high yield,...

Vrushabhendrappa; Singh, A.Kumar.; Balakrishna, K.; Sripathy, M.Harishchandra.; Batra, H.Vardhan., 2015: Studies on recombinant glucokinase (r-glk) protein of Brucella abortus as a candidate vaccine molecule for brucellosis. Brucellosis is one of the most prevalent zoonotic diseases of worldwide distribution caused by the infection of genus Brucella. Live attenuated vaccines such as B. abortus S19, B. abortus RB51 and B. melitensis Rev1 are found most effective agains...