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Botulinum toxin injection with and without electromyographic assistance for treatment of abducens nerve palsy: a pilot study


, : Botulinum toxin injection with and without electromyographic assistance for treatment of abducens nerve palsy: a pilot study. Journal of Aapos 12(3): 259-262

To compare the effects and complications of botulinum toxin injection into the medial rectus muscle with and without electromyographic (EMG) assistance for treatment of abducens nerve palsy. In a prospective, comparative, interventional case series, botulinum toxin was injected into the medial rectus muscle of 23 patients with esotropia secondary to abducens nerve palsy within 3 months of onset. Patients were randomly assigned to two groups. The injection was given with EMG assistance in the first (EMG group) and without EMG in the second group (no-EMG group). Success was defined as a distance esotropia of no more than 10(Delta) in the primary position. Angle of deviation was recorded preoperatively and at 1 week, 3 months, and 6 months; any postoperative complications and side effects were noted. There were 11 patients in the EMG and 12 patients in the no-EMG group. The ocular deviations were significantly improved in both groups with an overall 6 month success rate of 52.2% (p = 0.008 in the EMG group, p = 0.006 in the no-EMG group). Success rates and mean changes of the angle of deviation were not statistically different between the two groups. Postinjection blepharoptosis was found to be significantly more in the EMG group (p = 0.009). The effectiveness of botulinum toxin injection is the same with or without EMG assistance into the medial rectus muscle for treatment of abducens nerve palsy. EMG assistance is associated with more blepharoptosis.

US$19.90

PMID: 18396081

DOI: 10.1016/j.jaapos.2007.11.006


Other references

Osetskii A.I., 1986: Peculiarities of the kinetics of enzyme reactions in a viscous organic solvent medium. The relationship for the effective activation energy in non-diffusively controlled enzyme reactions has been obtained using a model of reversibly dissipation subsystems. In addition to parameters which describe the reaction potential barrier, an a...

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Targonsky, E.D.; Dai, F.; Koshkin, V.; Karaman, G.T.; Gyulkhandanyan, A.V.; Zhang, Y.; Chan, C.B.; Wheeler, M.B., 2006: alpha-lipoic acid regulates AMP-activated protein kinase and inhibits insulin secretion from beta cells. Aims/hypothesis: The antioxidant compound alpha-lipoic acid (alpha-LA) possesses antidiabetic and anti-obesity properties. In the hypothalamus, alpha-LA suppresses appetite and prevents obesity by inhibiting AMP-activated protein kinase (AMPK). Gi...

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Kimura, M.; Satoh, J.; Ueno, M.; Horikoshi, I.; Sakuragawa, N., 1983: Adsorption of thrombin to glass surfaces and resultant changes in its activity. Yakugaku Zasshi 103(4): 411-413

Shimizu, K., 1993: Effect of endurance running training on the structural and metabolic properties of partially denervated soleus muscle in rats. To estimate the influence of partial denervation on the skeletal muscle, a histochemical and biochemical study was performed on the soleus muscle. Partial denervation was carried out by cutting the proximal root of the nerve innervating the soleus...

Noriega, E.A.berto Aragon.; Juarez, A.R.sa Garcia., 2002: Occurrence of shrimp postlarvae Crustacea Penaeidae in the inlet channel of a shrimp farm of Sonora state Incidencia de postlarvas de camaron Crustacea Penaeidae en el canal de Ilamada de una granja camaronera del estado de Sonora. The objective of this survey was to assess the recruitment of shrimp postlarvae in the inlet channel of a shrimp farm and in the mouth of a coastal lagoon, Bahia de Guasimas, Sonora. Zooplankton sampling was carried out every 1 fourteen days, from...

Mochitate K.; Miura T., 1989: Metabolic enhancement and increase of alveolar macrophages induced by ozone. Male Wistar rats were exposed to 0.2 ppm ozone (O3) for 14 days and at intervals alveolar macrophages were collected by bronchoalveolar lavage to examine the effects of O3. The specific activities of glucose-6-phosphate dehydrogenase and glutathio...

Wrenzycki, C.; Wells, D.; Herrmann, D.; Miller, A.; Oliver, J.; Tervit, R.; Niemann, H., 2001: Nuclear transfer protocol affects messenger RNA expression patterns in cloned bovine blastocysts. The successful production of embryos by nuclear transfer (NT) employing cultured somatic donor cells depends upon a variety of factors. The objective of the present study was to investigate the effects (1) of two different activation protocols, (2...

Morgan, D.P.; Hetzler, H.L.; Slach, E.F.; Lin, L.I., 1977: Urinary excretion of paranitrophenol and alkyl phosphates following ingestion of methyl or ethyl parathion by human subjects. Nitrophenolic and alkyl phosphate metabolites of methyl and ethyl parathion in the urine of human subjects soon after doses of 1 to 4 mg have been ingested. Particular alkyl phosphates can serve as specific indices of absorption of the respective...