+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Changes of Foxp3(+); regulatory T cells in patients with acute coronary syndrome

, : Changes of Foxp3(+); regulatory T cells in patients with acute coronary syndrome. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 27(8): 893-895

To investigate the changes of Foxp3(+); (including CD4(+);Foxp3(+); and CD4(+);CD25(+);Foxp3(+);) regulatory T cells (Tregs) in patients with acute coronary syndrome (ACS). Forty-four ACS patients, twenty patients with stable angina (SA) and twenty-four control patients were enrolled. The percentages of the peripheral Tregs, Foxp3 mRNA and plasma level of TGF-β1 were measured by flow cytometry, real-time quantitative PCR and ELISA. The percentages of CD4(+);CD25(+);Foxp3(+); Tregs and CD4(+);Foxp3(+); Tregs, Foxp3 mRNA and plasma level of TGF-β1 significantly decreased in the ACS group as compared with those in the SA group and the controls (P<0.05), while there was no significant difference in the percentage of CD4(+);CD25(+); Tregs among all three groups. There are less Foxp3(+);Tregs, perhaps with impaired function, in ACS patients, which might contribute to plaque destabilization.


PMID: 21806889

Other references

Lee, H.C.roline; Peisach, J.; Wittenberg, J.B., 1993: The role of hydrogen bonding to bound dioxygen in oxygen binding properties of soybean leghemoglobin. Biophysical Journal 64(2 PART 2): A49

Prentice, R., 1970: More priority for overseas aid. The Pearson Report came out in favour of 1 per cent. of GNP as a target for all donor countries to maintain in their aid programmes by 1975 at the latest. In addition a second target of 0.7 per cent. flow of government aid by 1975 is advocated. In...

Beck J.G.; Berisford M.A., 1992: The effects of caffeine on panic patients response components of anxiety. Using a double-blind placebo design, the present investigation explored the effects of caffeine on specific response components of anxiety with 21 Panic Disorder (PD) patients and 18 matched normal controls (NC). Three physiological measures (bloo...

Crozatier, B.; Franklin, D.; Theroux, P.; Tomoike, H.; Sasayama, S.; Ross, J., 1977: Loss of regional ventricular postextrasystolic potentiation after coronary occlusion in dogs. Postextrasystolic potentiation following coronary artery occlusion was studied serially using pairs of ultrasonic crystals to measure regional myocardial function in control, marginally ischemic, and ischemic segments of the left ventricle in dogs...

Li, Y-Fei.; Wei, Y-Feng.; Tan, Y.; Kong, X-Fei.; Zhou, K.; Wu, Z-Min.; Liu, Y-Jin., 2014: Detection and removal of Hg2+ based on mesoporous silica material functionalized by naphthalimide in aqueous solution. An inorganic-organic silica material (SBA-15-1), prepared by immobilization of the naphthalimide derivative within the channels of the mesoporous silica material SBA-15, is characterized by several spectroscopic methods. SBA-15-1 can be used as a...

Barus, V.; Foitova, I.; Koubkova, B.; Hodova, I.; Simkova, A.; Nurcahyo, W., 2007: A new nematode, Pongobius hugoti gen. et sp n. from the orangutan Pongo abelii (Primates : Hominidae). Light and scanning electron microscopical examination and molecular analysis of pinworm samples collected from the Sumatran orangutan (Pongo abelii) from Sumatra (Indonesia) revealed the presence of a new taxon, Pongobius hugoti gen. et sp. n. (O...

Singh, J.M.; Gunz, A.C.; Dhanani, S.; Aghari, M.; MacDonald, R.D., 2016: Frequency, Composition, and Predictors of In-Transit Critical Events During Pediatric Critical Care Transport. Transport of pediatric patients is common due to healthcare regionalization. We set out to determine the frequency of in-transit critical events during pediatric critical care transport and identify factors associated with these events. Retrospect...

Levine J.H.; Spear J.F.; Prood C.; Kadish A.A.; D.L.ngen C.; Moore E.N., 1985: The importance of current pathway in ablation in vitro and in vivo correlates. American Heart Association Monograph (114): III-390

Mosteller, R.D., 1978: Evidence that glucose starvation-sensitive mutants are altered in the relB locus. Genetic mapping studies indicate that the relaxed-control mutants isolated on the basis of sensitivity to glucose starvation contain lesions in the relB locus. These mutants, which are sensitive to protein synthesis inhibitors such as sulfacetamid...

Rapoff, A.J.; Bhatavadekar, N.B.; Daegling, D.J., 2004: Image-based weighted measures of skeletal stiffness Case studies of great ape mandibles. American Journal of Physical Anthropology Supplement (38): 165