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Changes of stage, predictive factors and adjuvant treatment modalities in seminomatous testicular cancer from 1987 to 2007 and their impact on the status of metastasis, recurrence-free and overall survival: a single-center analysis

, : Changes of stage, predictive factors and adjuvant treatment modalities in seminomatous testicular cancer from 1987 to 2007 and their impact on the status of metastasis, recurrence-free and overall survival: a single-center analysis. Urologia Internationalis 87(3): 282-287

To observe the changing presentation of seminomatous testicular cancer (STC), placing particular emphasis on predictive factors with a view to evaluating their impact on the status of metastasis, recurrence-free survival (RFS) and overall survival (OAS). 180 patients with STC were evaluated retrospectively. Four study periods were generated and compared for changes. The data were analyzed for predictive factors for metastasis. Mean follow-up was 83 months (range 10-246, patients alive = 146). The number of STC patients increased constantly throughout 2007. From 1992 onwards, significantly more patients were diagnosed as being in CS1 (p = 0.001). The odds ratio (OR) of metastasis was significantly higher for pT3 than pT2 STC (OR 12.4 vs. 1.7; p = 0.003); pT1 tumors showed a lower risk factor. The 10- and 15-year RFS were 91 and 85%, respectively. Patients in clinical stages higher than CS1 (CS>1) had significantly reduced RFS (p < 0.001). The 5- and 10-year OAS were 97 and 96%, respectively. Patients in CS>1 had significantly reduced OAS rates (p = 0.013). The number of STC cases is increasing, particularly in the case of patients in CS1. This emphasizes the need for surveillance regimens and makes the evaluation of predictive factors for metastasis, recurrence and survival essential.


PMID: 21876335

DOI: 10.1159/000329768

Other references

Zielke, A.; Bolland, G.; Schnabel, G., 1965: Clinical and psychological tests on the effectiveness of a new geriatric drug. Das Deutsche Gesundheitswesen 20(34): 1570-1574

Kleiman, F.; Pietrokovsky, S.; Paraense, W.Lobato.; Wisnivesky-Colli, C., 2004: Southernmost finding of Lymnaea viatrix orbigny, 1835 (Pulmonata: Lymnaeidae), intermediate host of Fasciola hepatica (Linnaeus, 1758) (Trematoda: Digenea), in urban and rural areas of Patagonia, Argentina. We report the first finding of Lymnaea viatrix south of parallel 41 masculine S, in rural and urban areas from Argentina. Ninety snails were collected during year 2000, from a concrete pond at a Public Square in El Bolsón Village, Río Negro prov...

Tamaki, H.; Takahashi, H.; Fukayal, A.; Fukuda, M.; Arai, S.; Muraoka, D., 2005: The distributional patterns of Undaria pinnatifida (Harvey) Suringar and sea urchins related to water velocity condition in Ogatsu Bay, Miyagi Prefecture. This study was designed to investigate the mechanism for the loss of Undaria pinnatifida bed in Ogatsu Bay, Miyagi Prefecture. At the outer areas of the bay with high water velocity, U pinnatifida grew densely and sea urchins were scarce. In some...

Tyler David L., 1992: Taylor Ranch. Pages 317 1992

Kanski, M.; Garrison, B.J.; Postawa, Z., 2016: Effect of Oxygen Chemistry in Sputtering of Polymers. Molecular dynamics computer simulations are used to model kiloelectronvolt cluster bombardment of pure hydrocarbon [polyethylene (PE) and polystyrene (PS)] and oxygen-containing [paraformaldehyde (PFA) and polylactic acid (PLA)] polymers by 20 keV...

Anonymous, 1992: Joseph Lyn Andrews. American Journal of Orthodontics and Dentofacial Orthopedics 101(6): 569-569

Srolovitz; Scott, 1986: Clock-model description of incommensurate ferroelectric films and of nematic-liquid-crystal films. Physical Review. B, Condensed Matter 34(3): 1815-1819

Stephens, G.J.; Owen, D.G.; Opalko, A.; Pisano, M.R.; Mcgregor, W.H.; Robertson, B., 1995: Studies on the N-type inactivation of the mouse Kv11 channel induced by the Kv34 ball peptide. Society for Neuroscience Abstracts 21(1-3): 1829

Kitagawa, K.; Kohda, N.; Sugai, S.; Ogawa, T., 1997: Correlations of corneoconjunctival lesions to salivary disorders and autoantibodies in primary Sjogren's syndrome. We studied 87 cases of primary Sjogren's syndrome regarding the severity of keratoconjunctivitis sicca (KCS), salivary gland disorders and autoantibodies. The severity of KCS was positively associated with salivary scintigraphy, anti-SS-A ant...

Genestar, C.; Palou, J., 2006: SEM-FTIR spectroscopic evaluation of deterioration in an historic coffered ceiling. Microorganisms generally degrade wood when moisture, oxygen and other environmental factors provide favorable growing conditions. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were used to study the developm...