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Clinical analysis of minimal deviation adenocarcinoma of the cervix: a report of five cases


, : Clinical analysis of minimal deviation adenocarcinoma of the cervix: a report of five cases. Ai Zheng 27(12): 1310-1314

The minimal deviation adeno-carcinoma (MDA) of the cervix is a rare disease. The misdiagnosis rate of this disease is relatively high and there is no standard treatment for it. This study was to evaluate clinicopathologic features, diagnosis, and treatment of MDA. Records of five patients with MDA treated in the Second Affiliated Hospital of Sun Yet-sen University from Jan. 1991 to Dec. 2006 were retrospectively analyzed. The median age of the five patients was 47 years (range 38-59 years). The most common complaints included a large amount of watery discharge and atypical genital bleeding. Histology revealed that MDA was highly differentiated. Although the appearance of MDA glands was difficult to be distinguished from normal endocervical glands, the location of MDA glands was deeper than the lower level of normal endocervical glands. Carcinoembryonic antigen (CEA) and p53 in two patients were detected positive by immunohistochemistry. Four patients underwent surgery, among which one received surgery plus postoperative radiotherapy, and three received surgery plus postoperative chemotherapy and radiotherapy. One inoperable case received palliative radiotherapy. All cases were followed up for 6-88 month. Two patients achieved disease-free survival, one of which survived for more than five years. Three patients died of local recurrence and distant metastasis. Diagnosis of MDA mainly depends on its clinical manifestations and the pathological feature that MDA glands are located deeper than the lower level of normal endocervical glands. Surgery combined with other adjunct therapy achieves good outcomes for MDA.

US$29.90

PMID: 19080000


Other references

D.S.ntis, L.; Coticchio, G., 2011: Theoretical and experimental basis of slow freezing. In human IVF, cryopreservation of oocytes has become an alternative to embryo storage. It has also shown enormous potential for oocyte donation, fertility preservation and animal biotechnology. Mouse oocytes have represented the elective model to...

Togo Y., 1981: The structure of the shell of the fresh-water gastropod Cipangopaludina japonia; Mesogastropoda. Chishitsugaku Zasshi = Journal of the Geological Society of Japan 87(8): 519-526

Webster, A.G.; Humphries, R.K.; Robertson, P., 1995: The striped legless lizard Delma impar: case study of a threatened species recovery programme. Bennett, A. , Backhouse, G. , Clark, T. People And Nature Conservation: Perspectives On Private Land Use And Endangered Species Recovery. 29-34

Rivara, F.P., 1983: Epidemiology of violent deaths in children and adolescents in the United States. Injuries are the largest cause of death in children and adolescents after the first year of life. Injuries more than any other disease result in 3.5 million years of potential life lost. Poor children are particularly at risk of dying from trauma,...

Voorhees, R.M.; Ramakrishnan, V., 2013: Structural basis of the translational elongation cycle. The sequential addition of amino acids to a growing polypeptide chain is carried out by the ribosome in a complicated multistep process called the elongation cycle. It involves accurate selection of each aminoacyl tRNA as dictated by the mRNA codo...

Rosner, S.; Fuehrer, E., 1996: Studies on ecophysiological aspects of the hibernation of the Spruce sawfly, Pristiphora abietina Christ. Pristiphora abietina survives the winter as a nymph in a cocoon resting in the upper layer of soil litter. In order to understand the causes of doubtful nymph mortality, the cold resistance and some features related to it were tested by experiment...

Kara, A.; Trushin, O.; Yildirim, H.; Rahman, T.S., 2009: Off-lattice self-learning kinetic Monte Carlo: application to 2D cluster diffusion on the fcc(111) surface. We report developments of the kinetic Monte Carlo (KMC) method with improved accuracy and increased versatility for the description of atomic diffusivity on metal surfaces. The on-lattice constraint built into our recently proposed self-learning K...

Brewster, A.L.; Nelson, J.P.; McCanne, T.R.; Lucas, D.R.; Milner, J.S., 1998: Gender differences in physiological reactivity to infant cries and smiles in military families. The primary purpose of this experiment was to examine gender differences in physiological reactivity to infant cries and smiles in military families. Twenty males and 29 females viewed and listened to videotapes of a crying infant and a smiling in...

Kvitnitskaia, N.N., 1976: 70th birthday of Prof. N. N. Kvitnitskaia. Gigiena i Sanitariia: 117-117

Tabak, R.; Aquije, G.; Fisher, B.E., 2014: Aerobic exercise to improve executive function in Parkinson disease: a case series. Parkinson disease (PD) affects cognition, specifically executive function. In people with PD, impaired executive function has been identified as an indicator of fall risk and decreased quality of life. Therefore, it is important to consider impair...