+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Comparison on the long term outcome between endoscopic submucosal dissection and surgical treatment for undifferentiated early gastric cancer

, : Comparison on the long term outcome between endoscopic submucosal dissection and surgical treatment for undifferentiated early gastric cancer. Korean Journal of Gastroenterology 63(2): 90-98

There are controversies on the efficacy and safety of endoscopic submucosal dissection (ESD) for un-differentiated early gastric cancer (EGC) despite the expansion of ESD indications. The aim of this study was to evaluate the long term outcome of ESD compared to that of surgical treatment in patients with undifferentiated EGC. A total of 76 patients who underwent ESD for undifferentiated EGC and 149 patients who met the ESD indication and received surgical treatment from January 2005 to December 2010 at Chonnam National University Hwasun Hospital were included. In the ESD group, en bloc resection and complete resection were achieved in 84.2% (64/76) and 76.3% (58/76) of patients, respectively. Among these patients, 58 (76.3%) met the ESD indication (indication group), and the remaining 18 (23.7%) did not meet the ESD indication (above indication group). Complete resection rates for indication group and above indication group were 86.2% (50/58) and 44.4% (8/18), respectively (p<0.05). The mean follow-up period was 42.2 ± 19.2 months. Total recurrence rates in the ESD group and operation group were 14.1% (9/76) and 0.7% (1/149), respectively (p<0.05). The main complication of ESD was bleeding (5.2%, 4/76). In the operation group, 2 (1.3%) patients died from postoperative bleeding and leakage of anastomosis site. ESD may be a feasible and safe treatment modality compared to that of surgical treatment for undifferentiated EGC when managed according to the expanded criteria. However, close endoscopic surveillance is required in this group because of higher incidence of intragastric recurrence.


PMID: 24561695

Other references

Gobbel, G.T.; Kondziolka, D.; Fellows-Mayle, W.; Uram, M., 2011: Manual vs automated delivery of cells for transplantation: accuracy, reproducibility, and impact on viability. Cellular transplantation holds promise for the management of a variety of neurological disorders. However, there is great variability in cell type, preparation methods, and implantation technique, which are crucial to clinical outcomes. We compare...

Factor, S.A.; Molho, E.S., 2004: Threatening auditory hallucinations and Cotard syndrome in Parkinson disease. Psychotic symptoms are commonly reported in patients with Parkinson disease (PD). In particular, patients experience non-threatening visual hallucinations that can occur with insight (so called hallucinosis) or without. Auditory hallucinations are...

Livi, V.; Cancellieri, A.; Patelli, M.; Trisolini, R., 2013: Tracheobronchial involvement in Churg-Strauss syndrome. Journal of Bronchology & Interventional Pulmonology 19(1): 81-82

Debrabant, A.; Nakhasi, H., 2003: Programmed cell death in trypanosomatids: is it an altruistic mechanism for survival of the fittest?. The protozoan parasites Leishmania, Trypanosoma cruzi and Trypanosoma brucei show multiple features consistent with a form of programmed cell death (PCD). Despite some similarities with apoptosis of mammalian cells, PCD in trypanosomatid protozoan...

Brewer, G., 1981: Zinc supplementation treatment of growth retardation and hypogonadism in sickle cell patients. American Journal of Hematology 10(2): 195-198

Ruebenbauer, T., 1962: The phenomenon of heterosis in relation to the plasmon-genome interaction-a theoretical study. In order to explain the occurrence of reciprocal differences in degree of heterosis and the extinction of these differences that may occur in advanced generations, a theory of stimulation due to heterogeneity of plasmagenes is advanced. Formulae a...

Silvertown, J.; Poulton, P.; Johnston, E.; Edwards, G.; Heard, M.; Biss, P.M., 2006: The Park Grass Experiment 1856-2006: its contribution to ecology. The Park Grass Experiment, begun in 1856, is the oldest ecological experiment in existence. Its value to science has changed and grown since it was founded to answer agricultural questions. In recent times the experiment has shown inter alia how:...

Cavallero, G.; Rossi, E.; Dealessi, M.; Testa, S.; Zanardi, F.; Leinati, A.; Summa, M., 1991: Primary and secondary hyperparathyroidism. Analysis of our results. The Authors introduce their experience of primary and secondary surgical treatment of hyperparathyroidism, pointing out at first the good confidence of echography, scintigraphy and TAC, in the pre-operating diagnostic of the parathyroid glands loc...

Khan, S.Akhtar.; Waqas, M.; Ujjan, B.Uddin.; Salim, A.; Javed, G.; Ahmed, S.Ijlal.; Surani, M.; Khan, M., 2016: Providing Care Beyond the Hospital: Perspective of a Tertiary Care Hospital from a Developing Country. Neurorehabilitation is an important aspect of continuing care for neurosurgical patients with functional disability. In developing countries, where formal home nursing frequently is unavailable, ensuring care after discharge is a difficult task. T...

Shibata, M.; Ito, M.; Aoki, S.; Sakamoto, Y.; Nagao, S.; Fujita, K., 1991: Effect of the construction of power line on golden eagles - mechanisms of home range abandonment -. Strix, 10: 115-126