geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Complementary medicine in guidelines of the German Guideline Program in Oncology: comparison of the evidence base between complementary and conventional therapy. huebner@med.uni-frankfurt.de


, : Complementary medicine in guidelines of the German Guideline Program in Oncology: comparison of the evidence base between complementary and conventional therapy. huebner@med.uni-frankfurt.de. Journal of Cancer Research and Clinical Oncology 139(9): 1481-1488

The German Guideline Program in Oncology (GGPO) comprises guidelines aiming at epidemiology, prevention, diagnosis, treatment and aftercare of different types of cancer. As many patients in Germany use complementary and alternative medicine (CAM), the aim of our study was to assess the information on CAM presented in these guidelines compared to conventional, supportive and psychosocial therapy. We assessed all recommendations and statements from guidelines published from 2010 to 2012 from the program according to level of evidence (LoE) as given in the guideline. We differentiated between conventional cancer treatment, conventional supportive treatment, psychosocial interventions and complementary treatment. A total of 9 guidelines (ovarian, colorectal, pancreatic, gastric, breast, prostate, oral cancer, melanoma and Hodgkin lymphoma) were included in our analysis. The total number of statements is highly diverse, ranging from 35 to 150. Only few statements and recommendations are given regarding supportive, psychosocial or complementary therapy. Regarding conventional treatments, only two guidelines (ovarian and oral cancer) have more than 50 % statements and recommendations on level 1. Considering supportive treatments, the LoE is lower, except the guideline on pancreatic cancer (40 % level 1). In breast cancer, all statements are based on expert consensus. Four guidelines do not include any statement at all. All guidelines beside that on Hodgkin lymphoma include at least one statement or recommendation on psychosocial therapy. Most recommendations are GCP.CAM is discussed in 8 guidelines; LoE is low with GCP statements dominating. There may be different reasons for the low number of statements and recommendations on supportive, psychosocial and CAM therapies. Often, these topics are considered less important, and evidence is assumed as being low. In the GGPO, guidelines focusing on psychosocial and supportive therapy are under development. Thus, cancer-specific guidelines will be able to refer to these guidelines and only include recommendations on psychosocial care and supportive therapy which are specific for the type of cancer. A national guideline on CAM would close the gap of information for physicians and patients. In case of missing or low evidence, a transparent description of this uncertainty would be valuable information to professionals and patients.

US$19.90

PMID: 23817695

DOI: 10.1007/s00432-013-1464-7


Other references

Chrones, J., 2016: EMRs are here to stay, but ... Canadian Family Physician Medecin de Famille Canadien 61(5): 415-416

Anonymous, 1963: Wagin-a new wheat variety. Wagin (M121), from (Gabo x Doubbi) x Ben-cubbin3, is an early-midseason to midseason variety with stronger straw and higher flour quality than Bencubbin and good yields. It is resistant to Urocystis tritici but susceptible to Puccinia graminis.

Shamansky L.; Long X.; Miller M.M., 1988: Isolation and characterization of reticuloendotheliosis virus transformed bone marrow cells from congenic lines of chickens differing at the mhc. FASEB Journal 2(4): ABSTRACT 1086

Causey, N.B., 1961: Adrityla, a new milliped genus Chordeumidae Conotylidae. Psyche, 68: 131-136

Ghosh, AK.; Raychaudhuri, DN., 1973: Studies on the aphids (Homoptera: Aphididae) from eastern India 15. A study of Nipponaphis Pergande and related genera with descriptions of a new genus and eight new species from eastern lndia. Part l. Kontyu, 412: 148-165

Knudsen, F.; Andersen, P.T.; Nielsen, L.K.; Jersild, C., 1988: Complement and leukocyte changes during major vascular surgery. To gain further insight into the effects of major vascular surgery involving the abdominal aorta on complement and leukocytes, serial measurements of leukocyte and differential counts, plasma concentrations of C3d, and granulocyte elastase bound t...

Coutsis, John, G., 2004: Revision of the Turanana endymion species-group (Lycaeuidae). The separation of Turanana taygetica (Rebel, 1902) stat. n. from Turanana endymion (Freyer, 1850) is effected on the basis of small, but constant differences in their male genitalia, the absence of genitalia intermediates, as well as on the basis...

Kelekci, S.; Yilmaz, B.; Yakut, Y.; Yasar, L.; Savan, K.; Sonmez, S., 2006: Hormonal and ovarian stromal blood supply changes after laparoscopic tubal sterilization: a prospective controlled study. Objectives: The purpose of this study is to determine if the effects of tubal sterilization (TS) by laparoscopy have any risk of a subsequent significant decrease in ovarian reserve and vascular support within the ovary by means of stromal artery...

Anonymous, 2005: Update: syringe exchange programs--United States, 2002. Syringe exchange programs (SEPs) provide sterile syringes in exchange for used syringes to reduce transmission of human immunodeficiency virus (HIV) and other bloodborne infections associated with reuse of contaminated syringes by injection-drug u...

Wassmann, S.; Ribaudo, N.; Faul, A.; Laufs, U.; Böhm, M.; Nickenig, G., 2003: Effect of atorvastatin 80 mg on endothelial cell function (forearm blood flow) in patients with pretreatment serum low-density lipoprotein cholesterol levels <130 mg/dl. The effect of 6-week treatment with 80 mg/day atorvastatin on vascular function in the forearm was investigated in 18 patients with mean pretreatment serum low-density lipoprotein cholesterol concentrations of 112 +/- 4 mg/dl in a double-blind, pl...