+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Consequences of digital mammography in population-based breast cancer screening: initial changes and long-term impact on referral rates

, : Consequences of digital mammography in population-based breast cancer screening: initial changes and long-term impact on referral rates. European Radiology 20(9): 2067-2073

To investigate the referral pattern after the transition to full-field digital mammography (FFDM) in a population-based breast cancer screening programme. Preceding the nationwide digitalisation of the Dutch screening programme, an FFDM feasibility study was conducted. Detection and referral rates for FFDM and screen-film mammography (SFM) were compared for first and subsequent screens. Furthermore, radiological characteristics of referrals in digital screening were assessed. A total of 312,414 screening mammograms were performed (43,913 digital and 268,501 conventional), with 4,473 consecutive referrals (966 following FFDM). Initially the FFDM referral rate peaked, and many false-positive results were noted as a consequence of pseudolesions and increased detection of (benign) microcalcifications. A higher overall referral rate was observed in FFDM screening in both first and subsequent examinations (p < .001), with a significant increase in cancer detection (p = .010). As a result of initial inexperience with digital screening images implementing FFDM in a population-based breast cancer screening programme may lead to a strong, but temporary increase in referral. Dedicated training in digital screening for radiographers and screening radiologists is therefore recommended. Referral rates decrease and stabilise (learning curve effect) at a higher level than in conventional screening, yet with significantly enhanced cancer detection.


PMID: 20407901

DOI: 10.1007/s00330-010-1786-7

Other references

Deierhoi, R.J.; Dawes, L.G.; Vick, C.; Itani, K.M.F.; Hawn, M.T., 2013: Choice of intravenous antibiotic prophylaxis for colorectal surgery does matter. The Surgical Care Improvement Program endorses mandatory compliance with approved intravenous prophylactic antibiotics; however, oral antibiotics are optional. We hypothesized that surgical site infection (SSI) rates may vary depending on the choi...

Bjornson A.B.; Bjornson H.S.; Kitko B.P., 1980: Participation of normal human immuno globulin m immuno globulin g and immuno globulin a in opsono phagocytosis and intra cellular killing of bacteroides fragilis and bacteroides thetaiotaomicron by human polymorphonuclear leukocytes. Infection & Immunity 28(2): 633-637

Bleacher, J.E.; Glaze, L.S.; Greeley, R.; Hauber, E.; Baloga, S.M.; Sakimoto, S.E.H.; Williams, D.A.; Glotch, T.D., 2009: Spatial and alignment analyses for a field of small volcanic vents south of Pavonis Mons and implications for the Tharsis province, Mars. A field of small volcanic vents south of Pavonis Mons was mapped with each vent assigned a two-dimensional data point. Nearest neighbor and two-point azimuth analyses were applied to the resulting location data. Nearest neighbor results show that...

Meek, T.; Gittins, N.; Duggan, J.E., 1999: Cricoid pressure: knowledge and performance amongst anaesthetic assistants. We investigated the cricoid pressure technique of 135 anaesthetic assistants attending the annual conference of the British Association of Operating Department Assistants in May 1997. Their knowledge and training were assessed using a structured i...

Roch, K. le; Winzeler, E., 2005: The transcriptome of the malaria parasite Plasmodium falciparum. The different techniques used to analyse gene expression in P. falciparum, mechanisms controlling transcriptional or posttranscriptional activations in Plasmodium, and the use of the transcriptome in identifying new drug targets are discussed.

Mumford, F.E.; Stark, H.M.; Smith, D.H., 1963: 4-Hydroxybenzyl alcohol, a naturally occurring cofactor of indoleacetic acid oxidase. 4-Hydroxybenzyl alcohol, a previously unrecognized constituent of plants, has been isolated from muskmelon seedling extracts (Cucurbita moschata). The compound acts as a cofactor for indoleacetic acid oxidase both in vitro and in the oat coleoptil...

Davies, S.J.; Silver, J., 1999: Adult axon regeneration in adult CNS white matter. Trends in Neurosciences 21(12): 515-515

Charfi, K.; Grami, R.; Ben Jeddou, A.; Messaoudi, A.; Mani, Y.; Bouallegue, O.; Boujaafar, N.; Aouni, M.; Mammeri, H.; Mansour, Wène., 2017: Extended-spectrum β-lactamases and plasmid-mediated quinolone resistance in enterobacterial clinical isolates from neonates in Tunisia. This study was conducted to investigate extended-spectrum-β-lactamase (ESBL) producing Enterobacteriaceae isolates from the Center of Maternity and Neonatology of Monastir, Tunisia. Fourty-six strains out of 283 were found to produce ESBL: Klebsi...

Cortner, H.J.; Gardner, P.D.; Taylor, J.G.; Carpenter, E.H.; Zwolinski, M.J.; Daniel, T.C.; Stenberg, K.J., 1984: Uses of public opinion surveys in resource planning. A discussion of 3 independent published surveys used to measure public attitudes towards fire management in the USA, illustrating the range of survey design, sampling techniques, analytical methods, and the information that can be provided by surv...

Dexter, T.M., 1990: Introduction to the haemopoietic system. Cancer Surveys 9(1): 1-5