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Consolidation of glycosyl hydrolase family 30: a dual domain 4/7 hydrolase family consisting of two structurally distinct groups


, : Consolidation of glycosyl hydrolase family 30: a dual domain 4/7 hydrolase family consisting of two structurally distinct groups. Febs Letters 584(21): 4435-4441

In this work glycosyl hydrolase (GH) family 30 (GH30) is analyzed and shown to consist of its currently classified member sequences as well as several homologous sequence groups currently assigned within family GH5. A large scale amino acid sequence alignment and a phylogenetic tree were generated and GH30 groups and subgroups were designated. A partial rearrangement in the GH30 defining side-associated β-domain contributes to the differentiation of two major groups that contain up to eight subgroups. For this CAZy family of Clan A enzymes the dual domain fold is conserved, suggesting that it may be a requirement for evolved function. This work redefines GH family 30 and serves as a guide for future efforts regarding enzymes classified within this family.

US$19.90

PMID: 20932833

DOI: 10.1016/j.febslet.2010.09.051


Other references

Linberg, R.G.; Kraft, L.M.; Simmonds, R.C.; Bailey, O.T.; Dunlap, W.A.; Haymaker, W., 1975: The effects of cosmic particle radiation on pocket mice aboard Apollo XVII: II. Characteristics and tolerances of the pocket mouse and incidence of disease. Pocket mice are facultative homoiotherms with the ability to drop their metabolic rate dramatically while at rest or in response to environmental stresses. Under these conditions, they characteristically enter a state of prolonged torpor. These an...

Morere, P.; Ribes, A., 1953: A case of bronchial angiomatosis. Algerie Medicale 57(1): 82-84

Calle, D.; Negri, V.; Ballesteros, P.; Cerdán, Sán., 2015: Magnetoliposomes loaded with poly-unsaturated fatty acids as novel theranostic anti-inflammatory formulations. We describe the preparation, physico-chemical characterization and anti-inflammatory properties of liposomes containing the superparamagnetic nanoparticle Nanotex, the fluorescent dye Rhodamine-100 and omega-3 polyunsaturated fatty acid ethyl este...

Barrack, E.R.; Bujnovszky, P.; Walsh, P.C., 1983: Subcellular distribution of androgen receptors in human normal, benign hyperplastic, and malignant prostatic tissues: characterization of nuclear salt-resistant receptors. Two populations of nuclear androgen receptors have been characterized in human prostatic tissue, and the levels and proportions of each were found to differ in normal prostates, benign hyperplastic prostates (BPH), and malignant prostates. A signi...

Chen, S.R.ng; Dunigan, D.D.; Dickman, M.B., 2003: Bcl-2 family members inhibit oxidative stress-induced programmed cell death in Saccharomyces cerevisiae. Selected antiapoptotic genes were expressed in baker's yeast (Saccharomyces cerevisiae) to evaluate cytoprotective effects during oxidative stress. When exposed to treatments resulting in the generation of reactive oxygen species (ROS), inclu...

Rheinheimer, J., 1968: The human factor in accident prevention. American Association of Industrial Nurses Journal 16(5): 24-25

Brown, T., 2002: The HIV/AIDS epidemic in Asia. An assessment of the current human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) situation in Asia is presented. An estimate of its prevalence and mortality in selected countries at the end of 1999 is tabulated. The risk fa...

Glauert, H.P.; Robertson, L.W.; Silberhorn, E.M., 2001: PCBs and tumor promotion. Robertson, Larry W [Editor], Hansen, Larry G [Editor] PCBs: Recent Advances in Environmental Toxicology and Health Effects 355-371

Anonymous, 1983: Are Catholic hospitals morally responsible for surgical practices in associated office buildings?. Hospital Progress 64(5): 61-62

Anonymous, 1979: Notes from Cuba. The birth rate in Cuba has declined from 31.7 in 1967 to 17.7 in 1977. Accompanying this decline has been an increase in the abortion rate from 285/1000 live births in 1968 to 812 in 1976. This increase has followed increasingly liberal interpreta...