+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Controversies on the treatment strategy for rectal submucosal cancer: case series and review of the literature

, : Controversies on the treatment strategy for rectal submucosal cancer: case series and review of the literature. Digestive Endoscopy 25 Suppl 2: 2-5

Endoscopic submucosal dissection (SD) has emerged as one of the treatment strategies for submucosal rectal cancers. The present study reviewed the clinical outcomes of patients with rectal submucosal cancer treated by ESD. This was a retrospective review of four patients who had rectal tumor treated by ESD from 2010 to 2012 with histopathology showing T1 submucosal adenocarcinoma. The mean age (SD) was 69.5 (7.33) and the male to female ratio was 3:1. There were no post-ESD complications. The mean (SD) size of the tumors was 2.93 (0.87) cm. One patient with deep resection margin involvement received laparoscopic low anterior resection. Another with deep margin involvement of <1 mm refused surgery and was treated by chemoradiotherapy.There was no recurrence in all the cases with a mean follow-up duration of 461.3 (209.0) days. ESD was one of the important treatment strategies for T1sm-s rectal cancer especially when the risk of nodal metastasis was low. ESD spared the patient from colostomy when the T1 cancer was located in the lower third of the rectum. The role of adjuvant and neoadjuvant chemoradiotherapy remains controversial.


PMID: 23617640

DOI: 10.1111/den.12101

Other references

Chakrabarti C., 1977: The Pagladiya Basin; geomorphology and fluvial processes. Miscellaneous Publications, Geological Survey of India: ages 73-96. 1977.

Zav'yantsev, V.E., 1976: Transmissive drug resistance and colicinogenicity of escherichia coli strains isolated from piglets. Of 151 E. coli strains isolated from piglets which died of colibacillosis, only 26 were sensitive to chlortetracycline, chloramphenicol, neomycin, kanamycin, ampicillin and polymyxin; the other 125 were resistant to 1-4 of the antibiotics. Of the...

Hammer, G.L., 1998: Crop modelling: current status and opportunities to advance. Major issues in crop modelling, including the combination of a scientific approach to enhance understanding with an applications orientation to retain a focus on prediction and problem-solving, and achieving the appropriate balance between simplic...

Botwinick, J.; Brinley, J.F., 1962: Aspects of RT set during brief intervals in relation to age and sex. Journal of Gerontology 17: 295-301

Bromley, S.M.; Doty, R.L., 1993: Bilateral and unilateral assessment of odor recognition memory. Chemical Senses 18(5): 533-534

Kiyohara, C.; Wakai, K.; Mikami, H.; Sido, K.; Ando, M.; Ohno, Y., 2003: Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of environmental tobacco smoke and lung cancer: a case-control study in Japanese nonsmoking women. Genetic backgrounds may modify the association of environmental tobacco smoke (ETS) with lung cancer risk. Polymorphisms of both the activating and detoxifying enzymes, cytochrome P4501A1 (CYP1A1) and glutathione-S-transferase M1 (GSTM1), may be i...

Fraser, R.B.; Silverstone, P.I.; Familton, L., 1977: Investigating detrusor instability. Lancet 1(8017): 900-900

Faure, E.M.; Canaud, L.; Agostini, C.; Shaub, R.; Böge, G.; Marty-ané, C.; Alric, P., 2014: Reintervention after thoracic endovascular aortic repair of complicated aortic dissection. This study assessed predictive factors for reintervention after thoracic endovascular aortic repair (TEVAR) for complicated aortic dissection (C-AD). An institutional review of consecutive TEVAR for C-AD was performed. Between 2000 and 2011, 41 pa...

Narain, U.; Gupta, A., 2017: Urinary Tract Infection in Children with Nephrotic Syndrome. The occurrence of urinary tract infection (UTI) in nephrotic syndrome has been reported. However, the only causes for the infection reported to date are bacteria and prior reported series did not identify yeast or fungi as causative organisms. A r...

Rapin I., 1988: Children with inadequate language development management guidelines for otolaryngologists. Otolaryngologists are in the front line of physicians asked to evaluate children whose language development is lagging. The 4 most prevalent conditions to consider in the differential diagnosis are impaired hearing, mental deficiency, developmenta...