geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Covert reorganization of implicit task representations by slow wave sleep


, : Covert reorganization of implicit task representations by slow wave sleep. Plos One 4(5): E5675-E5675

There is evidence that slow wave sleep (SWS) promotes the consolidation of memories that are subserved by mediotemporal- and hippocampo-cortical neural networks. In contrast to implicit memories, explicit memories are accompanied by conscious (attentive and controlled) processing. Awareness at pre-sleep encoding has been recognized as critical for the off-line memory consolidation. The present study elucidated the role of task-dependent cortical activation guided by attentional control at pre-sleep encoding for the consolidation of hippocampus-dependent memories during sleep. A task with a hidden regularity was used (Number Reduction Task, NRT), in which the responses that can be implicitly predicted by the hidden regularity activate hippocampo-cortical networks more strongly than responses that cannot be predicted. Task performance was evaluated before and after early-night sleep, rich in SWS, and late-night sleep, rich in rapid eye movement (REM) sleep. In implicit conditions, slow cortical potentials (SPs) were analyzed to reflect the amount of controlled processing and the localization of activated neural task representations. During implicit learning before sleep, the amount of controlled processing did not differ between unpredictable and predictable responses, nor between early- and late-night sleep groups. A topographic re-distribution of SPs indicating a spatial reorganization occurred only after early, not after late sleep, and only for predictable responses. These SP changes correlated with the amount of SWS and were covert because off-line RT decrease did not differentiate response types or sleep groups. It is concluded that SWS promotes the neural reorganization of task representations that rely on the hippocampal system despite absence of conscious access to these representations. Original neurophysiologic evidence is provided for the role of SWS in the consolidation of memories encoded with hippocampo-cortical interaction before sleep. It is demonstrated that this SWS-mediated mechanism does not depend critically on explicitness at learning nor on the amount of controlled executive processing during pre-sleep encoding.

US$19.90

PMID: 19479080

DOI: 10.1371/journal.pone.0005675


Other references

Roessingh H.K., 1968: Panarctic Oils and all that; are there international implications?. Examines the historical, legal and international background to the question of Canadian sovereignty over the Queen Elizabeth and other Arctic Islands. Considers possible international implications which justify the unprecedented government partici...

Sampson, J.H.; Raghavan, R.; Brady, M.L.; Provenzale, J.M.; Herndon, J.E.; Croteau, D.; Friedman, A.H.; Reardon, D.A.; Coleman, R.Edward.; Wong, T.; Bigner, D.D.; Pastan, I.; Rodríguez-Ponce, Mía.Inmaculada.; Tanner, P.; Puri, R.; Pedain, C., 2007: Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions. Convection-enhanced delivery (CED) is a novel drug delivery technique that uses positive infusion pressure to deliver therapeutic agents directly into the interstitial spaces of the brain. Despite the promise of CED, clinical trials have demonstra...

Li, X.; Gorle, A.K.; Ainsworth, T.D.; Heimann, K.; Woodward, C.E.; Collins, J.Grant.; Keene, F.Richard., 2015: RNA and DNA binding of inert oligonuclear ruthenium(II) complexes in live eukaryotic cells. Confocal microscopy was used to study the intracellular localisation of a series of inert polypyridylruthenium(II) complexes with three eukaryotic cells lines - baby hamster kidney (BHK), human embryonic kidney (HEK-293) and liver carcinoma (Hep-G...

Ting, W.C., 1984: Circulating inhibitors. Non-specific circulating inhibitors detected in 13 patients did not result in significant bleeding episodes. Five non-haemophiliacs who had inhibitors to Factor VIIIC did not have any underlying disorders but all of them experienced major bleeding...

Subias I.; Fanlo I.; Yuste A.; Fernandez Nieto C., 1998: The Yenefrito Pb-Zn mine (Spanish central Pyrenees); an example of superimposed metallogenetic events. Three types of base metal deposits occur in the Devonian of the Central Pyrenees accompanying and post-dating the Hercynian orogeny. Since spatial and temporal relationships between mineralization can be recognized in the Yenefrito area, they have...

Byron, W.A., 1983: Respiratory function after paralysis of the right hemidiaphragm. We studied a 45-yr-old man with normal lung function before and 7 wk after right phrenic nerve crush. Total lung capacity, functional residual capacity, and forced vital capacity decreased with residual volume remaining unchanged. Static complianc...

Satarova, T.N., 2001: Alien gene transfer and inheritance at maize genetic transformation. Developments are discussed in genetic transformation in relation to specific cells, tissues and organs of maize as targets for alien gene transfer. Data are reviewed on genotypic peculiarities of transgenesis and inheritance of alien genes include...

Shulga, A.A.; Znamenskaya, L.V.; Morozova, O.V.; Leshchinskaya, I.B.; Kirpichnikov, M.P., 2000: Ribonuclease from Bacillus thuringiensis var. subtoxicus: Gene structure and regulation of biosynthesis. The gene for extracellular guanyl-specific ribonuclease of Bacillus thuringiensis var. subtoxicus (RNase Bth), a close homologue of the B. intermedius RNase (binase), was completely sequenced. Analysis of nucleotide sequences in the regions adjoin...

Interewicz, B.; Olszewski, W.L.; Stanislawska, J.; Sikora, M.; Durlik, M.; Maksymowicz, M., 2005: DNA released from rejecting organs is an indicator of the degree of graft cellular damage. Warm and cold ischemia as well as rejection of the transplanted organ or tissue cause destructive changes in the graft parenchyma. Fragments of disintegrated cellular organelles are phagocytized and digested by recipient scavenger cells in lymph n...

Shiota, S.; Takekawa, H.; Matsumoto, S-Ei.; Takeda, K.; Nurwidya, F.; Yoshioka, Y.; Takahashi, F.; Hattori, N.; Tabira, T.; Mochizuki, H.; Takahashi, K., 2014: Chronic intermittent hypoxia/reoxygenation facilitate amyloid-β generation in mice. Previous studies have shown a high prevalence of obstructive sleep apnea (OSA) among patients with Alzheimer's disease (AD). However, it is poorly assessed whether chronic intermittent hypoxia (CIH), which is a characteristic of OSA, affects...