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Cytotoxic constituents ofSorbaria sorbifolia var.stellipila

, : Cytotoxic constituents ofSorbaria sorbifolia var.stellipila. Archives of Pharmacal Research 20(1): 85-87

The acivity-guided fractionation upon the MeOH extract of the aerial parts ofSorbaria sorbifolia var.stellipila led to the isolation of two cucurbitacin-compounds, cucurbitacin D and cucurbitacin F, as active principles. Two compounds were shown to exhibit significant cytotoxicity against cultured human tumor cell lines, A-549, SK-OV-3, SK-MEL-2, XF-498, and HCT 15.


PMID: 18975218

DOI: 10.1007/BF02974048

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